SCHEMBL4392845

SCHEMBL4392845

Cc1ccc(-c2ccc(I)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
KIF11 P52732 1/20 0.38
PTGS2 P35354 1/20 0.38
MCL1 Q07820 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.35
TSHR P16473 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19004134 1.00 ACHE (0.50) ACHETDP1CYP2D6CYP2C9HPGD
SCHEMBL17469595 1.00 ACHE (0.50) ACHETDP1CYP2D6CYP2C9HPGD
SCHEMBL10068159 0.92 ACHE (0.42) ACHETDP1CYP2D6CYP2C9HPGD
SCHEMBL158 0.90
SCHEMBL2757577 0.90
SCHEMBL17078009 0.87
Bromide SCHEMBL3346674 0.87
Ammonia Solution, Strong SCHEMBL11574766 0.87
Fluoride SCHEMBL752726 0.87 ACHE (0.57) ACHETDP1ALDH1A1CA1CA2
SCHEMBL10634092 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085300-B Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2023-09-15 CN claimed
CN-114085300-A Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2022-02-25 CN claimed
WO-2024035622-A1 INHIBITORS OF cGAS ACTIVITY AS THERAPEUTIC AGENTS BELLBROOK LABS, LLC (US) 2024-02-15 WO disclosed
US-20240023434-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2024-01-18 US disclosed
US-20230312481-A1 SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF ARBUTUS BIOPHARMA CORP (CA) 2023-10-05 US disclosed
WO-2023181962-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, AND IMAGE DISPLAY DEVICE 三菱ケミカル株式会社 2023-09-28 WO disclosed
CN-114085300-B Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2023-09-15 CN disclosed
US-11744146-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-11732138-B2 Deep ultraviolet-excitable water-solvated polymeric dyes BECTON, DICKINSON AND COMPANY (US) 2023-08-22 US disclosed
US-20230235177-A1 Deep Ultraviolet-Excitable Water-Solvated Polymeric Dyes BECTON, DICKINSON AND COMPANY 2023-07-27 US disclosed
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-5160487-A Tetraarylbenzidine derivative as charge transport compound HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-11-03 US disclosed
EP-0475676-A1 Electrophotographic member HITACHI CHEMICAL CO., LTD. (JP) 1992-03-18 EP disclosed
US-4898800-A DURABILITY RICOH COMPANY, LTD. (JP) 1990-02-06 US disclosed
EP-0119067-B1 PROCESS FOR PREPARING ALDEHYDES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-26 EP disclosed
US-4607116-A FROM DIARYLIODONIUM SALT NIPPON PETROCHEMICALS COMPANY LIMITED (JP) 1986-08-19 US disclosed
EP-0119065-B1 PROCESS FOR PREPARING DIARYLS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-08-13 EP disclosed
US-4590281-A REACTING DIARYLIODONIUM SALT WITH UNSATURATED ALCOHOL NIPPON PETROCHEMICALS COMPANY (JP) 1986-05-20 US disclosed
EP-0119065-A1 Process for preparing diaryls NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-09-19 EP disclosed
EP-0119067-A1 Process for preparing aldehydes NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNT1, C9 ACHE 1136/4885TDP1 3142/4885CYP2D6 634/4885
US-11744146-B2 Amine-based compound and organic light-emitting device including the same AOC2, AOC1, EML4 ACHE 37/4885TDP1 1125/4885CYP2D6 2096/4885
US-20230312481-A1 SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF NSD3, PML, NSD1 ACHE 4527/4885TDP1 3167/4885CYP2D6 2178/4885
US-20240023434-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, AOX1 ACHE 2015/4885TDP1 4217/4885CYP2D6 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.