Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 7/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383084 | 0.89 | LMNA (0.56) | LMNAHPGDHSD17B10NPC1KCNA3 | |
| SCHEMBL8435929 | 0.69 | KCNA3 (0.64) | LMNAHPGDNPC1KCNA3PKM | |
| SCHEMBL4393225 | 0.69 | KCNA3 (0.59) | LMNANPC1KCNA3PKMKMT2A | |
| SCHEMBL8436388 | 0.68 | KCNA3 (0.63) | LMNAHPGDHSD17B10NPC1KCNA3 | |
| SCHEMBL20529368 | 0.67 | KCNA3 (0.60) | LMNAHPGDNPC1KCNA3PKM | |
| SCHEMBL13615748 | 0.65 | LMNA (0.56) | LMNAHPGDHSD17B10NPC1KMT2A | |
| SCHEMBL9460076 | 0.64 | PKM (0.55) | LMNAHPGDHSD17B10NPC1PKM | |
| SCHEMBL11131932 | 0.64 | PKM (0.51) | LMNAHPGDHSD17B10NPC1KCNA3 | |
| SCHEMBL13615127 | 0.64 | ALDH1A1 (0.53) | LMNAHPGDHSD17B10NPC1PKM | |
| Saccharin SCHEMBL7361433 | 0.63 | ALDH1A1 (0.53) | LMNAHPGDHSD17B10KCNA3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |