Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436589 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTLMNAHPGD | |
| SCHEMBL439021 | 0.78 | KMT2A (0.55) | ALDH1A1KMT2AMAPTLMNAHPGD | |
| SCHEMBL442244 | 0.78 | ACHE (0.43) | ALDH1A1KMT2AMAPTLMNARAD52 | |
| SCHEMBL438613 | 0.78 | BCHE (0.45) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL440698 | 0.76 | TP53 (0.50) | ALDH1A1KMT2AMAPTLMNAHPGD | |
| SCHEMBL437551 | 0.75 | NR4A2 (0.51) | — | |
| SCHEMBL439853 | 0.75 | BCHE (0.43) | LMNATYMS | |
| SCHEMBL439635 | 0.74 | APP (0.48) | ALDH1A1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL437947 | 0.73 | KMT2A (0.53) | ALDH1A1KMT2AMAPTLMNAHPGD | |
| SCHEMBL21359345 | 0.73 | ALDH1A1 (0.37) | ALDH1A1KMT2AMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |