Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | USP13 | Q92995 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439004 | 0.86 | ACHE (0.43) | ACHEMAP4K4BACE1 | |
| SCHEMBL438613 | 0.81 | BCHE (0.45) | BCHEACHEGRIN1GRIN2ABACE1 | |
| SCHEMBL10385174 | 0.81 | BCHE (0.45) | BCHEACHEGRIN1GRIN2APARP1 | |
| SCHEMBL437551 | 0.79 | NR4A2 (0.51) | BCHEACHEGRIN1GRIN2APARP1 | |
| SCHEMBL442244 | 0.79 | ACHE (0.43) | BCHEACHEGRIN1GRIN2APARP1 | |
| SCHEMBL20494939 | 0.79 | PARP1 (0.41) | BCHEACHEGRIN1GRIN2APARP1 | |
| SCHEMBL439645 | 0.79 | ACHE (0.46) | BCHEACHEGRIN1GRIN2APARP1 | |
| SCHEMBL29391085 | 0.79 | PARP1 (0.41) | BCHEACHEGRIN1GRIN2APARP1 | |
| SCHEMBL436530 | 0.78 | BACE1 (0.42) | MAP4K4BACE1AXLCCNCCDK8 | |
| SCHEMBL439366 | 0.75 | ALDH1A1 (0.46) | TYMSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |