Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.34 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405338 | 0.93 | TERT (0.36) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1DRD2 | |
| SCHEMBL4400739 | 0.92 | GUCY1B2 (0.37) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1DRD2 | |
| SCHEMBL4412712 | 0.91 | LMNA (0.36) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1DRD2 | |
| SCHEMBL4400766 | 0.89 | TERT (0.37) | DRD2SLC6A4PARP1HTR7HTR1A | |
| SCHEMBL4404430 | 0.89 | HTR4 (0.37) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1DRD2 | |
| SCHEMBL4398650 | 0.89 | GUCY1B2 (0.35) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1DRD2 | |
| SCHEMBL4406787 | 0.88 | PARP1 (0.37) | PARP1HTR7HTR1AKMT2AACHE | |
| SCHEMBL4405829 | 0.88 | PARP1 (0.37) | PARP1HTR7HTR1AKMT2AACHE | |
| SCHEMBL913758 | 0.87 | KMT2A (0.41) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1DRD2 | |
| SCHEMBL4411263 | 0.84 | SLC6A3 (0.37) | DRD2HTR1AKMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |