Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405338 | 0.96 | TERT (0.36) | TERTDRD2ADRA2AADRA2BADRA2C | |
| SCHEMBL4412712 | 0.96 | LMNA (0.36) | TERTDRD2ADRA2AADRA2BADRA2C | |
| SCHEMBL4404430 | 0.93 | HTR4 (0.37) | DRD2SLC6A4PARP1PARP2HTR7 | |
| SCHEMBL4400739 | 0.90 | GUCY1B2 (0.37) | DRD2SLC6A4PARP1HTR7HTR1A | |
| SCHEMBL4396907 | 0.89 | GUCY1B2 (0.34) | DRD2SLC6A4PARP1HTR7HTR1A | |
| SCHEMBL4403759 | 0.89 | HTR1A (0.37) | DRD2SLC6A4PARP1HTR1A | |
| SCHEMBL4396585 | 0.88 | LMNA (0.40) | ADRA2ASLC6A4PARP1HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL4411256 | 0.87 | HTR7 (0.40) | TERTDRD2PARP1HTR7HTR1A | |
| SCHEMBL4398650 | 0.86 | GUCY1B2 (0.35) | DRD2SLC6A4PARP1HTR7HTR1A | |
| SCHEMBL4404435 | 0.86 | TERT (0.39) | TERTPARP1HTR7HTR1AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |