Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748003 | 1.00 | TRPA1 (0.41) | TRPA1TSHRADRA2AADRA2CKDM4E | |
| SCHEMBL12157425 | 1.00 | TRPA1 (0.41) | TRPA1TSHRADRA2AADRA2CKDM4E | |
| SCHEMBL20437579 | 0.84 | ADRB1 (0.33) | TRPA1TSHRADRA2AADRA2CKDM4E | |
| SCHEMBL8762226 | 0.81 | GABRA1 (0.36) | TRPA1TSHRKDM4ETHRBLMNA | |
| SCHEMBL7644979 | 0.79 | ADRA2A (0.41) | ADRA2AADRA2CKDM4ETHRBLMNA | |
| SCHEMBL734869 | 0.78 | ALOX5 (0.38) | KDM4EALDH1A1ALOX5 | |
| SCHEMBL15689666 | 0.78 | IDO1 (0.39) | LMNAALDH1A1 | |
| SCHEMBL8763614 | 0.78 | TRPA1 (0.39) | TRPA1TSHRADRA2AADRA2CKDM4E | |
| SCHEMBL96935 | 0.77 | HCAR2 (0.43) | ADRA2AADRA2CKDM4ETHRBLMNA | |
| SCHEMBL16970750 | 0.77 | HCAR2 (0.43) | ADRA2AADRA2CKDM4ETHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156778-B2 | Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-10-13 | — | — | US | disclosed |
| US-20120322053-A1 | CROSS-COUPLED PEPTIDE NUCLEIC ACIDS FOR DETECTION OF NUCLEIC ACIDS OF PATHOGENS | APPELLA DANIEL H (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120107794-A1 | Cross-Coupled Peptide Nucleic Acids for Detection of Nucleic Acids of Pathogens | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2012-05-03 | — | — | US | disclosed |