SCHEMBL4400744

SCHEMBL4400744

C=CC(=O)OC(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 6/20 0.34
HSD17B10 Q99714 1/20 0.34
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL25408153 0.80 LMNA (0.50) HSD17B10LMNA
SCHEMBL3171987 0.79 KEAP1 (0.35)
SCHEMBL6889394 0.79 KEAP1 (0.35)
SCHEMBL10025691 0.78 ALDH1A1 (0.34) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL29014391 0.78 THRB (0.32) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL10718030 0.75 TSHR (0.37) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL4641581 0.75
SCHEMBL779461 0.75 ALDH1A1 (0.32) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL278164 0.74
SCHEMBL52 0.74 CA2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 US claimed
WO-2020132057-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2020-06-25 WO claimed
US-20090305071-A1 Fluoro-compound water repellent composition for wood product dimensional stability ZHANG JUN 2009-12-10 US claimed
US-20070160850-A1 Fluoro-compound water repellent composition for wood product dimensional stability OSMOSE, INC. (US) 2007-07-12 US claimed
WO-2007067648-A2 FLUORO-COMPOUND WATER REPELLENT COMPOSITION FOR WOOD PRODUCT DIMENSIONAL STABILITY OSMOSE, INC. (US) 2007-06-14 WO claimed
US-20260132143-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF AMGEN INC. (US) 2026-05-14 US disclosed
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same DAIKIN INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
US-20250260063-A1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, SECONDARY BATTERY, AND LITHIUM-ION SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2025-08-14 US disclosed
EP-3780232-B1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, LITHIUM-ION SECONDARY BATTERY, AND MODULE DAIKIN IND LTD (JP) 2025-07-30 EP disclosed
US-20250174720-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
US-12315885-B2 Electrolytic solution, electrochemical device, lithium-ion secondary battery, and module DAIKIN INDUSTRIES, LTD. (JP) 2025-05-27 US disclosed
EP-4553940-A1 SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2025-05-14 EP disclosed
WO-2020132057-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2020-06-25 WO disclosed
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 US disclosed
US-20170214087-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND SECONDARY BATTERY NEC CORPORATION (JP) 2017-07-27 US disclosed
US-20170214087-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND SECONDARY BATTERY NEC CORPORATION (JP) 2017-07-27 US disclosed
US-20090305071-A1 Fluoro-compound water repellent composition for wood product dimensional stability ZHANG JUN 2009-12-10 US disclosed
US-20070160850-A1 Fluoro-compound water repellent composition for wood product dimensional stability OSMOSE, INC. (US) 2007-07-12 US disclosed
WO-2007067648-A2 FLUORO-COMPOUND WATER REPELLENT COMPOSITION FOR WOOD PRODUCT DIMENSIONAL STABILITY OSMOSE, INC. (US) 2007-06-14 WO disclosed
CN-1163567-A Method for reducing uterine nutritional effects of tamoxifen and tamoxifen analogues LILLY CO ELI (US) 1997-10-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132143-A1 HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF KRAS, NRAS, HRAS ALDH1A1 2638/4885TP53 10/4885HIF1A 2972/4885
US-20250174720-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE HCN2, HCN1, HCN3 ALDH1A1 955/4885TP53 2950/4885HIF1A 4609/4885
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same ASH2L, OLA1, ODC1 ALDH1A1 1584/4885TP53 3646/4885HIF1A 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.