Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405558 | 0.93 | HTR4 (0.39) | PARP1KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL4396585 | 0.90 | LMNA (0.40) | PARP1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4403744 | 0.87 | PARP1 (0.42) | PARP1HTR1AHTR7 | |
| SCHEMBL4409085 | 0.87 | LMNA (0.40) | PARP1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4401804 | 0.87 | PARP1 (0.40) | PARP1HTR1AHTR7 | |
| SCHEMBL4400766 | 0.86 | TERT (0.37) | TERTPARP1HTR1AHTR7FAAH | |
| SCHEMBL913081 | 0.85 | KMT2A (0.43) | PARP1HTR1AHTR7 | |
| SCHEMBL4400741 | 0.85 | L3MBTL1 (0.39) | TERTKDM4ERXFP1FAAH | |
| SCHEMBL4394218 | 0.84 | CCR8 (0.41) | HTR1AHTR7MCHR1FAAH | |
| SCHEMBL4405338 | 0.84 | TERT (0.36) | TERTPARP1HTR1AHTR7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |