Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404435 | 0.93 | TERT (0.39) | PARP1KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL4401901 | 0.90 | HTR4 (0.46) | HTR4KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL4402091 | 0.90 | LMNA (0.42) | HTR4PARP1HTTCCR8HTR1A | |
| SCHEMBL4551166 | 0.90 | LMNA (0.42) | HTR4PARP1HTTCCR8HTR1A | |
| SCHEMBL4405631 | 0.86 | SSTR4 (0.40) | HTR4HTR1AHTR7 | |
| SCHEMBL4404430 | 0.86 | HTR4 (0.37) | HTR4EPHX1PARP1HTR1AHTR7 | |
| SCHEMBL4409097 | 0.86 | CCR8 (0.44) | HPGDCCR8SMN1; SMN2 | |
| SCHEMBL914678 | 0.85 | KMT2A (0.45) | HTR4PARP1KDM4EHSD17B10HTR1A | |
| SCHEMBL4403841 | 0.85 | CCR8 (0.39) | HTR4KDM4ECCR8 | |
| SCHEMBL4403442 | 0.85 | ADRB2 (0.40) | HTR4PARP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |