Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.42 |
| ▸ | BRAF | P15056 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 7/20 | 0.38 |
| ▸ | SRC | P12931 | 6/20 | 0.38 |
| ▸ | SYK | P43405 | 6/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416963 | 0.92 | MAPK14 (0.44) | MAPK14BRAFF10GSK3ASRC | |
| SCHEMBL5497982 | 0.86 | MAPK14 (0.52) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL4419919 | 0.84 | SMN1; SMN2 (0.45) | MAPK14BRAF | |
| SCHEMBL4417785 | 0.83 | MAPK14 (0.43) | MAPK14BRAFF10GSK3ALYN | |
| SCHEMBL4417851 | 0.82 | MAPK14 (0.44) | MAPK14F10GSK3ASRCSYK | |
| SCHEMBL4416273 | 0.81 | MAPK14 (0.41) | MAPK14GSK3ASRCSYK | |
| SCHEMBL5490019 | 0.80 | RAB9A (0.42) | MAPK14GSK3A | |
| SCHEMBL4726185 | 0.79 | BRAF (0.42) | MAPK14BRAFGSK3ALYNMAPK9 | |
| SCHEMBL4408299 | 0.78 | MAPK14 (0.42) | MAPK14GSK3ASRCSYKCYP3A4 | |
| SCHEMBL14534449 | 0.77 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |