Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659103 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| SCHEMBL15234281 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| Urea SCHEMBL28285830 | 0.85 | CA2 (0.59) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| SCHEMBL698879 | 0.84 | CA1 (0.62) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| SCHEMBL698880 | 0.84 | CA1 (0.62) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| SCHEMBL2796740 | 0.84 | CA1 (0.62) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| SCHEMBL1686722 | 0.83 | GAA (0.58) | SMN1; SMN2ALDH1A1RAB9AHPGDCA1 | |
| SCHEMBL9943346 | 0.83 | GAA (0.58) | SMN1; SMN2ALDH1A1RAB9AHPGDCA1 | |
| SCHEMBL5700509 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD | |
| SCHEMBL15833197 | 0.81 | HPGDS (0.61) | SMN1; SMN2ALDH1A1RAB9ASLC1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856031-B1 | 2-ARYLPROPIONIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-02-25 | — | — | EP | claimed |
| CN-117203198-A | Compounds as PU.1 inhibitors | 浙江星浩澎博医药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-3719011-B1 | PYRAZOLE AMIDE COMPOUND HAVING PESTICIDAL ACTIVITY AND USE THEREOF | JIANGSU FLAG CHEM IND CO LTD (CN) | 2023-03-29 | — | — | EP | disclosed |
| CN-109988149-B | Pyrazole amide compound with insecticidal activity and application thereof | 江苏中旗科技股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20200329707-A1 | PYRAZOLAMIDE COMPOUND HAVING INSECTICIDAL ACTIVITY AND USE THEREOF | JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) | 2020-10-22 | — | — | US | disclosed |
| EP-3719011-A1 | PYRAZOLE AMIDE COMPOUND HAVING PESTICIDAL ACTIVITY AND USE THEREOF | Jiangsu Flag Chemical Industry Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |
| US-20200206321-A1 | METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-07-02 | — | — | US | disclosed |
| EP-3075729-B1 | PYRAZOLE AMIDE COMPOUND AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2019-01-02 | — | — | EP | disclosed |
| US-9723838-B2 | Pyrazolyl amide compounds and uses thereof | Shenyang Sinochem Agrochemicals R&D Co., LTD (CN) | 2017-08-08 | — | — | US | disclosed |
| US-20160286806-A1 | PYRAZOLYL AMIDE COMPOUNDS AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2016-10-06 | — | — | US | disclosed |
| EP-3075729-A1 | PYRAZOLE AMIDE COMPOUND AND APPLICATION THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2016-10-05 | — | — | EP | disclosed |
| EP-1037868-A2 | $g(a)-HYDROXY, -AMINO, AND HALO DERIVATIVES OF $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999026909-A2 | ALPHA-HYDROXY, -AMINO AND -FLUORO DERIVATIVES OF BETA-SULPHONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
| EP-0775140-A1 | SPIRO-SUBSTITUTED AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005203-A1 | SPIRO-SUBSTITUTED AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206321-A1 | METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS | ELANE, MPO, MMP8 | SMN1; SMN2 1157/4885ALDH1A1 994/4885RAB9A 2391/4885 |
| US-20160286806-A1 | PYRAZOLYL AMIDE COMPOUNDS AND USES THEREOF | GTF3C1, GTF3C2, GTF3C4 | SMN1; SMN2 2923/4885ALDH1A1 2142/4885RAB9A 263/4885 |
| US-20200329707-A1 | PYRAZOLAMIDE COMPOUND HAVING INSECTICIDAL ACTIVITY AND USE THEREOF | KCNH1, CA3, KCNH3 | SMN1; SMN2 4572/4885ALDH1A1 1066/4885RAB9A 1413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.