SCHEMBL441035

SCHEMBL441035

C=CC(=O)N(CO)CN(CO)C(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
LMNA P02545 1/20 0.32
TSHR P16473 3/20 0.31
ALDH1A1 P00352 4/20 0.31
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224019 0.89
Water SCHEMBL11778100 0.86 ZDHHC20 (0.40) ZDHHC20ZDHHC2LMNATSHRALDH1A1
SCHEMBL11349202 0.84 ZDHHC20 (0.43) ZDHHC20ZDHHC2LMNATSHRALDH1A1
SCHEMBL11326347 0.80 ALDH1A1 (0.46) ZDHHC20ZDHHC2LMNATSHRALDH1A1
SCHEMBL4650592 0.80 LMNA (0.35) ZDHHC20ZDHHC2LMNATSHR
SCHEMBL6667461 0.80 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHR
SCHEMBL423989 0.80
SCHEMBL11557201 0.78 ZDHHC20 (0.37) ZDHHC20ZDHHC2TSHRALDH1A1
SCHEMBL422327 0.78 ZDHHC20 (0.47) ZDHHC20ZDHHC2TSHRALDH1A1
SCHEMBL7170704 0.75 CA12 (0.43) ZDHHC20ZDHHC2LMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4259671-A1 COPOLYMER HAVING VISCOELASTIC AND SUSPENSIVE PROPERTIES COATEX (FR) 2023-10-18 EP claimed
WO-2022123127-A1 COPOLYMER HAVING VISCOELASTIC AND SUSPENSIVE PROPERTIES COATEX (FR) 2022-06-16 WO claimed
US-8784786-B2 Rheology modifier polymer RHODIA OPERATIONS (FR) 2014-07-22 US claimed
US-3936441-A Process for the production of water adsorbing but water-insoluble cellulose ethers HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
EP-3784706-B1 PREPARATION OF AN ACTIVE POLYMER EMULSION COATEX SAS (FR) 2024-04-03 EP disclosed
US-20240010775-A1 COPOLYMER HAVING VISCOELASTIC AND SUSPENSIVE PROPERTIES COATEX (FR) 2024-01-11 US disclosed
EP-4259671-A1 COPOLYMER HAVING VISCOELASTIC AND SUSPENSIVE PROPERTIES COATEX (FR) 2023-10-18 EP disclosed
US-11382844-B2 Shampoo composition and method of use CONOPCO, INC. (US) 2022-07-12 US disclosed
US-11376209-B2 Antidandruff composition and method of use CONOPCO, INC. (US) 2022-07-05 US disclosed
WO-2022123127-A1 COPOLYMER HAVING VISCOELASTIC AND SUSPENSIVE PROPERTIES COATEX (FR) 2022-06-16 WO disclosed
US-20210196614-A1 ANTIDANDRUFF COMPOSITION AND METHOD OF USE CONOPCO, INC., D/B/A UNILEVER 2021-07-01 US disclosed
EP-3784706-A1 PREPARATION OF AN ACTIVE POLYMER EMULSION Coatex (FR) 2021-03-03 EP disclosed
US-4171705-A Cigarette filter HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed
EP-0003599-A1 Organic phosphorus compounds with 2-hydroxyalkylphosphoric acid groups, process for their preparation and their use as flame retardants HOECHST AKTIENGESELLSCHAFT (DE) 1979-08-22 EP disclosed
US-4117222-A PROCESS FOR THE MANUFACTURE OF ABSORBENT, MODIFIED STARCH ETHERS AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4096289-A Electrostatic deposition of swellable, modified cellulose ether on water wet hydrophilic substrate HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed
US-4072776-A PHOSPHOROUS CONTAINING ACRYLIC ACID ESTERS HOECHST AKTIENGESELLSCHAFT (DT) 1978-02-07 US disclosed
US-4066828-A Process for the production of water-adsorbing cellulose ethers HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4015611-A OF CELLULOSE ETHERS HOECHST AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3936441-A Process for the production of water adsorbing but water-insoluble cellulose ethers HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11376209-B2 Antidandruff composition and method of use ACR, SMURF1, POLR1C ZDHHC20 773/4885ZDHHC2 928/4885LMNA 2494/4885
US-20210196614-A1 ANTIDANDRUFF COMPOSITION AND METHOD OF USE ACR, SMURF1, POLR1C ZDHHC20 773/4885ZDHHC2 928/4885LMNA 2494/4885
US-11382844-B2 Shampoo composition and method of use CUTA, PCNA, ACR ZDHHC20 1560/4885ZDHHC2 1530/4885LMNA 1013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.