Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458413 | 0.81 | PDK2 (0.43) | PDK2VNN1NPC1RAB9A | |
| SCHEMBL3984591 | 0.77 | PDK1 (0.43) | RAB9A | |
| SCHEMBL4456609 | 0.77 | L3MBTL3 (0.49) | PDK2L3MBTL1 | |
| SCHEMBL1921739 | 0.77 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL4352484 | 0.77 | ACHE (0.59) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28291394 | 0.77 | CHRM2 (0.42) | L3MBTL1CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL4056659 | 0.74 | PDK2 (0.38) | PDK2VNN1NPC1RAB9A | |
| SCHEMBL1115239 | 0.74 | HPGD (0.47) | NPC1SMN1; SMN2 | |
| SCHEMBL969710 | 0.74 | HPGD (0.52) | NPC1 | |
| SCHEMBL27804524 | 0.74 | LMNA (0.56) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664049-B1 | SYNTHESIS OF PROTECTED PYRROLOBENZODIAZEPINES | SPIROGEN LTD (GB) | 2009-12-23 | — | — | EP | disclosed |