SCHEMBL4414548

SCHEMBL4414548

CC(C)(C)Cn1nnc(C(F)(F)F)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4405408 0.86 CNR1 (0.30) CNR1CNR2
SCHEMBL4408001 0.83 CNR1 (0.32) CNR1CNR2
SCHEMBL24425233 0.80
SCHEMBL4405551 0.80 CNR1 (0.31) CNR1CNR2
SCHEMBL4406010 0.79 SMN1; SMN2 (0.39) ALDH1A1LMNA
SCHEMBL4404340 0.77
SCHEMBL4406971 0.77 CNR1 (0.33) CNR1CNR2
SCHEMBL4407390 0.76 RECQL (0.39) ALDH1A1LMNA
SCHEMBL18937681 0.75
SCHEMBL4407109 0.74 TRPV1 (0.40) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
US-11718584-B2 Process for the synthesis anthranilic diamide compounds and intermediates thereof PI INDUSTRIES LTD. (IN) 2023-08-08 US disclosed
US-20220185782-A1 A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2022-06-16 US disclosed
US-20220144814-A1 A PROCESS FOR PREPARING ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2022-05-12 US disclosed
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718584-B2 Process for the synthesis anthranilic diamide compounds and intermediates thereof DAO, DDC, QDPR ALDH1A1 914/4885LMNA 2013/4885CNR1 3202/4885
US-20220185782-A1 A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF DAO, DDC, QDPR ALDH1A1 1089/4885LMNA 2222/4885CNR1 3152/4885
US-20220144814-A1 A PROCESS FOR PREPARING ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF F12, IDH3B, CA7 ALDH1A1 557/4885LMNA 819/4885CNR1 755/4885
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ARG1, NQO2 ALDH1A1 797/4885LMNA 3246/4885CNR1 1841/4885
US-20230339844-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ACMSD, ADCY10 ALDH1A1 968/4885LMNA 3519/4885CNR1 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.