Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonamide SCHEMBL4418171 | 0.95 | CA2 (0.49) | ALDH1A1MAPTCA2CA1MEN1 | |
| SCHEMBL21653874 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPTCA2CA1MEN1 | |
| SCHEMBL24994346 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTCA2CA1MEN1 | |
| SCHEMBL11103294 | 0.78 | CA1 (0.66) | ALDH1A1MAPTCA2CA1CA12 | |
| SCHEMBL632638 | 0.77 | POLB (0.55) | ALDH1A1MAPTCA2MEN1KMT2A | |
| SCHEMBL12789664 | 0.77 | EPHX1 (0.60) | CA2CA1MEN1KMT2AHTT | |
| Methane SCHEMBL11118664 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTCA2CA1MEN1 | |
| SCHEMBL11100453 | 0.75 | POLB (0.62) | ALDH1A1CA2CA1MEN1KMT2A | |
| SCHEMBL232188 | 0.74 | MAPT (0.78) | ALDH1A1MAPTCA2HTTCA12 | |
| SCHEMBL216185 | 0.74 | PTPN1 (0.62) | ALDH1A1CA2CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318563-A1 | Nematicidal Compositions and Methods | DIVERGENCE, INC. | 2009-12-24 | — | — | US | disclosed |
| WO-2006060654-A2 | PESTICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050203067-A1 | Pesticidal compositions and methods | DIVERGENCE, INC. | 2005-09-15 | — | — | US | disclosed |
| US-20040254150-A1 | Nematicidal compositions and methods | DIVERGENCE, INC. | 2004-12-16 | — | — | US | disclosed |
| WO-2004103070-A2 | NEMATICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254150-A1 | Nematicidal compositions and methods | NISCH, PNMT, ATL3 | ALDH1A1 1882/4885MAPT 2603/4885CA2 3445/4885 |
| US-20050203067-A1 | Pesticidal compositions and methods | ACHE, DDT, PTMS | ALDH1A1 3205/4885MAPT 3378/4885CA2 701/4885 |
| US-20090318563-A1 | Nematicidal Compositions and Methods | NISCH, PNMT, HNMT | ALDH1A1 1760/4885MAPT 2690/4885CA2 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.