Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4269734 | 0.90 | PTGS2 (0.42) | PPARGPPARAPTGS2 | |
| SCHEMBL4562509 | 0.80 | TAS1R3 (0.40) | TAS1R3TAS1R1POLBSMN1; SMN2 | |
| SCHEMBL4266898 | 0.80 | PPARG (0.52) | TAS1R3TAS1R1POLBSMN1; SMN2TSHR | |
| SCHEMBL10424846 | 0.77 | ITGB3 (0.47) | POLBSMN1; SMN2KMT2AMTNR1AMTNR1B | |
| SCHEMBL4265985 | 0.75 | PPARG (0.62) | POLBPPARGPPARA | |
| SCHEMBL6961103 | 0.72 | KMT2A (0.50) | POLBSMN1; SMN2TSHRKMT2AMTNR1A | |
| SCHEMBL28338828 | 0.72 | KMT2A (0.50) | POLBSMN1; SMN2TSHRKMT2AMTNR1A | |
| SCHEMBL9319017 | 0.72 | CTRC (0.42) | PPARGPPARAPTGS2 | |
| SCHEMBL11828506 | 0.71 | HSD17B10 (0.51) | POLBHTTNPSR1HPGD | |
| SCHEMBL4562510 | 0.71 | MEN1 (0.45) | SMN1; SMN2KMT2AHTTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046736-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2009-04-15 | — | — | EP | claimed |
| WO-2008014430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-01-31 | — | — | WO | claimed |