Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732878 | 0.88 | GPR84 (0.44) | MEN1KMT2AATMGAATBXA2R | |
| SCHEMBL4562509 | 0.76 | TAS1R3 (0.40) | ALDH1A1FFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22868096 | 0.75 | TAS1R3 (0.43) | HPGDALDH1A1FFAR1SLC6A2SLC6A3 | |
| SCHEMBL9109127 | 0.75 | ALOX5 (0.48) | MEN1KMT2AATMHPGDALDH1A1 | |
| SCHEMBL19732884 | 0.74 | PPARG (0.40) | MEN1KMT2AATMHPGDALDH1A1 | |
| SCHEMBL7566814 | 0.72 | FFAR1 (0.48) | MEN1KMT2AHPGDALDH1A1FFAR1 | |
| SCHEMBL7067078 | 0.72 | MMP9 (0.46) | MMP13ALOX5PPARGPPARA | |
| SCHEMBL4414978 | 0.71 | TAS1R3 (0.42) | MEN1KMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL14117471 | 0.70 | HTT (0.70) | MEN1KMT2AATMHPGDALDH1A1 | |
| SCHEMBL9738451 | 0.70 | HPGD (0.37) | MEN1KMT2AHPGDALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046736-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2009-04-15 | — | — | EP | claimed |
| WO-2008014430-A1 | ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-01-31 | — | — | WO | claimed |