SCHEMBL442011

SCHEMBL442011

O=C(O)c1cc(S(=O)(=O)c2ccccc2)c2c(c1C(=O)O)C(=O)OC2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
GAA P10253 2/20 0.40
POLB P06746 1/20 0.40
GFER P55789 1/20 0.40
ALDH1A1 P00352 2/20 0.38
ATM Q13315 2/20 0.38
ERAP1 Q9NZ08 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTR6 P50406 2/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37
MMP14 P50281 1/20 0.37
MMP16 P51512 1/20 0.37
MCL1 Q07820 2/20 0.36
MEN1 O00255 1/20 0.36
PABPC1 P11940 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189911 0.84 NPSR1 (0.40) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL7185210 0.82 NPSR1 (0.43) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL689428 0.80 NPSR1 (0.46) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL9308849 0.77 GAA (0.46) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL247392 0.72 HNF4A (0.46) ALDH1A1ATMMCL1MEN1KMT2A
SCHEMBL29676384 0.71 NPSR1 (0.47) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL34677 0.71 NPSR1 (0.47) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL4923819 0.71 NPSR1 (0.47) NPSR1GAAPOLBGFERALDH1A1
SCHEMBL505289 0.70 MMP2 (0.58) NPSR1POLBALDH1A1HTR6MMP1
Biphenyl SCHEMBL5672703 0.70 PTPN1 (0.45) ATMMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415447-A1 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP claimed
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
EP-2925804-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES Chevron Oronite Company LLC (US) 2015-10-07 EP disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
WO-2014085047-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES CHEVRON ORONITE COMPANY LLC (US) 2014-06-05 WO disclosed
US-8735040-B2 Toner, developer, and image forming apparatus RICOH COMPANY, LTD. (JP) 2014-05-27 US disclosed
US-20130171550-A1 TONER, DEVELOPER, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2013-07-04 US disclosed
US-20120065357-A1 RESIN FOR USE IN TONER, AND TONER AND DEVELOPER USING THE RESIN RICOH COMPANY, LTD. (JP) 2012-03-15 US disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
EP-2033984-B1 Heat-curable polyimide silicone composition and a cured film therefrom SHINETSU CHEMICAL CO (JP) 2011-01-19 EP disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed
EP-2033984-A2 Heat-curable polyimide silicone composition and a cured film therefrom Shin-Etsu Chemical Co., Ltd. (JP) 2009-03-11 EP disclosed
US-6638352-B2 For use in printed circuit boards; semiconductors HITACHI, LTD. (JP) 2003-10-28 US disclosed
US-6638631-B2 Stress relieving films comprising crosslinked mixtures of polysiloxanes, polyimides, polyamideimides copolymers and/or polyamides used as interfaces for semiconductors or printed circuits HITACHI, LTD. (JP) 2003-10-28 US disclosed
US-20030049193-A1 For use in printed circuit boards; semiconductors HITACHI,L TD (JP) 2003-03-13 US disclosed
US-20030047351-A1 Stress relieving films comprising crosslinked mixtures of polysiloxanes, polyimides, polyamideimides copolymers and/or polyamides used as interfaces for semiconductors or printed circuits SATSU YUICHI (JP) 2003-03-13 US disclosed
EP-0280801-B1 COLORLESS TRANSPARENT POLYIMIDE SHAPED ARTICLES AND PROCESS FOR THEIR PRODUCTION NITTO DENKO CORPORATION (JP) 1992-06-24 EP disclosed
EP-0415447-A1 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030049193-A1 For use in printed circuit boards; semiconductors ASIC1, ASIC3, RIOK2 NPSR1 3052/4885GAA 2564/4885POLB 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.