SCHEMBL7185210

SCHEMBL7185210

O=C(O)c1ccc(S(=O)(=O)c2ccccc2)c2c1C(=O)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 4/20 0.40
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
HTR6 P50406 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.38
GFER P55789 1/20 0.38
WDR5 P61964 1/20 0.38
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ERAP1 Q9NZ08 1/20 0.37
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
TYMS P04818 1/20 0.36
MMP1 P03956 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442011 0.82 NPSR1 (0.41) NPSR1ALDH1A1GAAKDM4EPKM
SCHEMBL15757935 0.79 TYMS (0.50) ALDH1A1KDM4EHPGDL3MBTL1LMNA
SCHEMBL29603070 0.79 TYMS (0.50) ALDH1A1KDM4EHPGDL3MBTL1LMNA
SCHEMBL7189911 0.75 NPSR1 (0.40) NPSR1ALDH1A1GAAKDM4ELMNA
SCHEMBL4923819 0.73 NPSR1 (0.47) NPSR1ALDH1A1GAAKDM4EPKM
SCHEMBL4962919 0.73 NPSR1 (0.47) NPSR1ALDH1A1GAAKDM4EPKM
SCHEMBL3192467 0.72 HTR6 (0.46) NPSR1GAAHTR6POLBGFER
SCHEMBL505289 0.72 MMP2 (0.58) NPSR1ALDH1A1HTR6POLBTSHR
SCHEMBL4802119 0.70 HNF4A (0.49) ALDH1A1KDM4EL3MBTL1LMNAMAPT
SCHEMBL8061969 0.70 HTR6 (0.50) NPSR1ALDH1A1GAAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6638631-B2 Stress relieving films comprising crosslinked mixtures of polysiloxanes, polyimides, polyamideimides copolymers and/or polyamides used as interfaces for semiconductors or printed circuits HITACHI, LTD. (JP) 2003-10-28 US disclosed
US-6638352-B2 For use in printed circuit boards; semiconductors HITACHI, LTD. (JP) 2003-10-28 US disclosed
US-20030047351-A1 Stress relieving films comprising crosslinked mixtures of polysiloxanes, polyimides, polyamideimides copolymers and/or polyamides used as interfaces for semiconductors or printed circuits SATSU YUICHI (JP) 2003-03-13 US disclosed
US-20030049193-A1 For use in printed circuit boards; semiconductors HITACHI,L TD (JP) 2003-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030049193-A1 For use in printed circuit boards; semiconductors ASIC1, ASIC3, RIOK2 NPSR1 3052/4885ALDH1A1 4510/4885GAA 2564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.