Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561555 | 0.88 | TLR8 (0.39) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1156315 | 0.85 | ALDH1A1 (0.54) | TLR8ALDH1A1GAAPDE4APDE4B | |
| SCHEMBL7698040 | 0.83 | XDH (0.41) | ALDH1A1 | |
| SCHEMBL7698039 | 0.83 | XDH (0.41) | ALDH1A1 | |
| SCHEMBL4420240 | 0.80 | TLR8 (0.34) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29956372 | 0.79 | POLB (0.44) | ALDH1A1GAAPDE4APDE4BPDE4C | |
| SCHEMBL2802409 | 0.79 | POLB (0.44) | ALDH1A1GAAPDE4APDE4BPDE4C | |
| SCHEMBL2557878 | 0.78 | CA1 (0.43) | TLR8MCHR1ENPP2FFAR1CA1 | |
| SCHEMBL2559821 | 0.78 | FFAR1 (0.50) | ENPP2LPLLIPGFFAR1CA1 | |
| SCHEMBL5147675 | 0.78 | TLR8 (0.45) | TLR8ALDH1A1GAAPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-7723455-B2 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1656408-B1 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| US-20050038223-A1 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| EP-1232225-B1 | SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-12-01 | — | — | EP | disclosed |
| EP-1381639-B1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-09-08 | — | — | EP | disclosed |
| US-20040135131-A1 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1427768-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| EP-1381639-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2003020790-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2002077060-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |
| EP-1232225-A1 | SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES | Covion Organic Semiconductors GmbH (DE) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034722-A1 | SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | ALDH1A2, SELE, PPOX | TLR8 996/4885ALDH1A1 87/4885GAA 3333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.