Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP12 | P39900 | 4/20 | 0.41 |
| ▸ | MMP14 | P50281 | 4/20 | 0.41 |
| ▸ | MMP15 | P51511 | 4/20 | 0.41 |
| ▸ | MMP16 | P51512 | 4/20 | 0.41 |
| ▸ | MMP26 | Q9NRE1 | 4/20 | 0.41 |
| ▸ | MMP7 | P09237 | 4/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413279 | 0.83 | TAS2R14 (0.45) | TAS2R14MMP1MMP9MMP2MMP12 | |
| SCHEMBL13973166 | 0.83 | TAS2R14 (0.45) | TAS2R14MMP1MMP9MMP2MMP12 | |
| SCHEMBL4424185 | 0.81 | LMNA (0.42) | MMP9MMP2 | |
| SCHEMBL4421998 | 0.81 | CA1 (0.46) | FKBP1APOLBTDP1L3MBTL1 | |
| SCHEMBL6507930 | 0.80 | NPSR1 (0.43) | TAS2R14MMP1MMP9MMP2MMP12 | |
| SCHEMBL4416979 | 0.80 | TAS2R14 (0.46) | TAS2R14MMP1MMP9MMP2MMP12 | |
| SCHEMBL4418766 | 0.79 | MTNR1B (0.51) | FKBP1APOLBTDP1L3MBTL1MTNR1B | |
| SCHEMBL4414378 | 0.79 | PKM (0.41) | TAS2R14FKBP1AMTNR1BGRIN2C | |
| SCHEMBL4411990 | 0.77 | ALDH1A1 (0.47) | FKBP1A | |
| SCHEMBL4413290 | 0.76 | ALDH1A1 (0.41) | FKBP1APOLBGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663983-B1 | N-SUBSTITUTED, 6,8-DIALKOXY-1,2,3,4-TETRAHYDRO-1H-ISOQUINOLINE AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2009-01-21 | — | — | EP | disclosed |
| US-20050070570-A1 | Novel potassium channels modulators | 4SC AG (DE) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070570-A1 | Novel potassium channels modulators | HCN4, KCNA4, KCNN4 | TAS2R14 514/4885MMP1 4692/4885MMP9 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.