Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433888 | 0.91 | KDM4E (0.53) | BRS3KDM4E | |
| SCHEMBL4437699 | 0.86 | SLC6A3 (0.55) | BRS3KDM4EPTGDR2LIPGFFAR1 | |
| SCHEMBL4438825 | 0.84 | BRS3 (0.42) | BRS3KDM4ELTB4R2 | |
| SCHEMBL4430746 | 0.84 | CYP1A2 (0.48) | BRS3KDM4ESLC6A4SLC6A3 | |
| SCHEMBL3917621 | 0.78 | DAO (0.46) | BRS3KDM4E | |
| SCHEMBL4438513 | 0.78 | KDM4E (0.47) | KDM4ESLC6A4SLC6A3 | |
| SCHEMBL4432530 | 0.77 | KDM4E (0.47) | KDM4E | |
| SCHEMBL4428820 | 0.77 | KDM4E (0.47) | KDM4E | |
| SCHEMBL4430684 | 0.77 | RXRA (0.41) | BRS3KDM4E | |
| SCHEMBL4429595 | 0.77 | KDM4E (0.40) | BRS3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125739-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |