SCHEMBL443111

SCHEMBL443111

Cc1cccc(-n2c(-c3ccccc3)c3ccccc3c2-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.51
KMT2A Q03164 4/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
MEN1 O00255 2/20 0.47
PLA2G1B P04054 1/20 0.47
HPGD P15428 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
ALDH1A1 P00352 5/20 0.46
POLB P06746 2/20 0.46
RAB9A P51151 2/20 0.44
NOTUM Q6P988 1/20 0.44
ADORA1 P30542 2/20 0.43
TP53 P04637 2/20 0.43
MAPT P10636 2/20 0.43
PMM2 O15305 1/20 0.43
MPI P34949 1/20 0.43
PHOSPHO1 Q8TCT1 1/20 0.43
ADORA3 P0DMS8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443186 0.82 LMNA (0.43) GAAKMT2ALMNASMN1; SMN2L3MBTL1
SCHEMBL443170 0.80 KDM4E (0.52) GAAKMT2ALMNASMN1; SMN2L3MBTL1
SCHEMBL445355 0.79 ALDH1A1 (0.48) SMN1; SMN2HPGDALDH1A1RAB9AMAPK1
SCHEMBL443120 0.79 SMN1; SMN2 (0.56) KMT2ASMN1; SMN2HPGDALDH1A1NOTUM
SCHEMBL31070137 0.79 ABCG2 (0.48) GAAKMT2ALMNASMN1; SMN2MEN1
SCHEMBL443171 0.78 MGLL (0.45) GAAKMT2ASMN1; SMN2L3MBTL1MEN1
SCHEMBL24063242 0.78 GAA (0.45) GAAKMT2ALMNASMN1; SMN2L3MBTL1
SCHEMBL442621 0.76 ALDH1A1 (0.40) GAALMNAHPGDALDH1A1RAB9A
SCHEMBL443047 0.76 POLB (0.38) KMT2ASMN1; SMN2L3MBTL1MEN1HPGD
SCHEMBL444779 0.76 SMN1; SMN2 (0.49) GAAKMT2ALMNASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-20120064443-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2012-03-15 US disclosed
US-20120064443-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2012-03-15 US disclosed