Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ME2 | P23368 | 1/20 | 0.33 |
| ▸ | ME1 | P48163 | 1/20 | 0.33 |
| ▸ | ME3 | Q16798 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240107 | 0.84 | CHKA (0.49) | DRD4DRD2DRD3ALDH1A1KMT2A | |
| SCHEMBL4422645 | 0.79 | DRD2 (0.56) | DRD4DRD2DRD3ME2ME1 | |
| SCHEMBL3112641 | 0.78 | DDB1 (0.55) | MEN1ALDH1A1KMT2A | |
| SCHEMBL16216149 | 0.78 | GRM5 (0.43) | DRD4DRD2DRD3GRM5TSHR | |
| SCHEMBL10305090 | 0.78 | ADRB1 (0.46) | DRD4DRD2DRD3TSHRALDH1A1 | |
| SCHEMBL3819497 | 0.77 | MAPT (0.40) | ALDH1A1KMT2ACHKACTSLCTSB | |
| Hydrochloric Acid SCHEMBL3108154 | 0.77 | ADRB1 (0.45) | DRD4DRD2DRD3TSHRALDH1A1 | |
| SCHEMBL3122680 | 0.76 | GRM5 (0.53) | GRM5MEN1ALDH1A1KMT2AME2 | |
| SCHEMBL3110614 | 0.75 | CHIA (0.52) | DRD4DRD2DRD3GRM5ALDH1A1 | |
| SCHEMBL13179270 | 0.75 | KDM4E (0.49) | TSHRMEN1ALDH1A1KMT2ACHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |