Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431363 | 0.84 | DRD4 (0.41) | CHKAALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL16216149 | 0.81 | GRM5 (0.43) | ALDH1A1KDM4EGAAMAPTGFER | |
| SCHEMBL10305090 | 0.81 | ADRB1 (0.46) | NCF1ALDH1A1KDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL3108154 | 0.80 | ADRB1 (0.45) | NCF1ALDH1A1KDM4EDRD2DRD4 | |
| SCHEMBL3122680 | 0.80 | GRM5 (0.53) | ALDH1A1KDM4EGAAMAPTGFER | |
| SCHEMBL3110614 | 0.79 | CHIA (0.52) | ALDH1A1KDM4EGAAMAPTDRD2 | |
| SCHEMBL16218812 | 0.78 | DRD2 (0.59) | ALDH1A1KDM4EGAAMAPTADRA2C | |
| SCHEMBL3112641 | 0.76 | DDB1 (0.55) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL20340801 | 0.76 | CHKA (0.53) | CHKANCF1ALDH1A1KDM4EGAA | |
| SCHEMBL111714 | 0.74 | GAA (0.62) | CHKANCF1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241509-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | CHKA 40/4885NCF1 3501/4885ALDH1A1 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.