Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216149 | 0.86 | GRM5 (0.43) | GRM5KDM4ELMNAGAAMAPT | |
| SCHEMBL3122680 | 0.82 | GRM5 (0.53) | GRM5KDM4ELMNAGAAMAPT | |
| SCHEMBL3115543 | 0.81 | CHIA (0.55) | CHIAESRRGKDM4ELMNAGAA | |
| SCHEMBL16218813 | 0.80 | CHIA (0.49) | CHIAESRRGKDM4ELMNAGAA | |
| SCHEMBL3118473 | 0.79 | CHIA (0.56) | CHIAESRRGKDM4ELMNAGAA | |
| SCHEMBL24240107 | 0.79 | CHKA (0.49) | KDM4ELMNAGAAMAPTDRD2 | |
| SCHEMBL16218815 | 0.78 | CHIA (0.55) | CHIAESRRGKDM4ELMNAGAA | |
| SCHEMBL3112641 | 0.76 | DDB1 (0.55) | ESRRGKDM4ELMNAGAAMAPT | |
| SCHEMBL10305090 | 0.76 | ADRB1 (0.46) | KDM4ELMNADRD2DRD4DRD3 | |
| SCHEMBL4431363 | 0.75 | DRD4 (0.41) | GRM5DRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12324845-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250161500-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20220288243-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-09-15 | — | — | US | disclosed |
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20200397927-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-12-24 | — | — | US | disclosed |
| EP-2474525-B1 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING INC (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-2474523-B1 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING INC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-2753605-B1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-2474523-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474526-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474525-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474524-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | CHIA 2788/4885GRM5 2084/4885ESRRG 570/4885 |
| US-20220288243-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | CHIA 2788/4885GRM5 2084/4885ESRRG 570/4885 |
| US-11241509-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | CHIA 3114/4885GRM5 1812/4885ESRRG 483/4885 |
| US-20250161500-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | CHIA 2788/4885GRM5 2084/4885ESRRG 570/4885 |
| US-12324845-B2 | Ligands for imaging cardiac innervation | CHRNB4, RXFP4, RXFP3 | CHIA 3045/4885GRM5 353/4885ESRRG 196/4885 |
| US-20200397927-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | CHIA 211/4885GRM5 1069/4885ESRRG 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.