Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444779 | 0.84 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL443060 | 0.81 | LMNA (0.57) | MAPTSMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL30845909 | 0.78 | MAPT (0.66) | MAPTSMN1; SMN2HPGDKMT2ACACNA2D1 | |
| SCHEMBL445312 | 0.78 | TP53 (0.45) | MAPTSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL13743638 | 0.77 | MAPT (0.60) | MAPTSMN1; SMN2HPGDKMT2ACACNA2D1 | |
| SCHEMBL443170 | 0.76 | KDM4E (0.52) | MAPTSMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL445355 | 0.75 | ALDH1A1 (0.48) | SMN1; SMN2HPGDALDH1A1MAPK1RAB9A | |
| SCHEMBL5004588 | 0.75 | KMT2A (0.59) | MAPTSMN1; SMN2HPGDKMT2ACACNA2D1 | |
| SCHEMBL5008115 | 0.75 | CACNA2D1 (0.77) | SMN1; SMN2HPGDCACNA2D1 | |
| SCHEMBL9152440 | 0.74 | LTA4H (0.68) | MAPTSMN1; SMN2HPGDALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809543-B2 | Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus | RICOH COMPANY, LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809543-B2 | Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus | RICOH COMPANY, LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20120064443-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120064443-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2012-03-15 | — | — | US | disclosed |