Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290411 | 0.85 | LDHA (0.58) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL7298435 | 0.85 | LDHA (0.58) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL10776070 | 0.85 | LDHA (0.58) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL6344277 | 0.83 | CYP3A4 (0.71) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL1047459 | 0.81 | MMP1 (0.44) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL5660141 | 0.80 | DPP4 (0.50) | — | |
| SCHEMBL11695436 | 0.79 | ALOX15 (0.66) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL7306975 | 0.79 | ALOX15 (0.48) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL27835674 | 0.79 | FOS (0.51) | MMP1CYP3A4FOSTTRJUN | |
| SCHEMBL27853740 | 0.79 | FOS (0.51) | MMP1CYP3A4FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |