SCHEMBL1047459

SCHEMBL1047459

COc1cc(CC(N)OC)ccc1F

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.44
CYP3A4 P08684 1/20 0.44
FOS P01100 1/20 0.42
TTR P02766 1/20 0.42
JUN P05412 1/20 0.42
NR3C1 P04150 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
LDHA P00338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419411 0.84 LDHA (0.57) CYP3A4FOSTTRJUNNR3C1
SCHEMBL1048622 0.81 FOS (0.44) MMP1CYP3A4FOSTTRJUN
SCHEMBL8180097 0.81 FOS (0.50) MMP1CYP3A4FOSTTRJUN
SCHEMBL4432280 0.81 MMP1 (0.53) MMP1CYP3A4FOSTTRJUN
SCHEMBL1083505 0.80 HTR2A (0.45) FOSTTRJUNNR3C1HSD17B1
SCHEMBL1048328 0.80 PNMT (0.46) MMP1CYP3A4FOSTTRJUN
SCHEMBL1067852 0.80 HTR1A (0.45) MMP1CYP3A4FOSTTRJUN
SCHEMBL14655562 0.80 MBOAT4 (0.41) MMP1CYP3A4FOSTTRJUN
SCHEMBL1047457 0.79 TAAR1 (0.50) FOSTTRJUNNR3C1HSD17B1
SCHEMBL27835674 0.78 FOS (0.51) MMP1CYP3A4FOSTTRJUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-20 US claimed
EP-4313030-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS Terran Biosciences, Inc. (US) 2024-02-07 EP claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
EP-2884962-B1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INT LLC (US) 2019-05-01 EP claimed
US-20150216799-A1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC 2015-08-06 US claimed
EP-2884962-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS Smartek International LLC (US) 2015-06-24 EP claimed
WO-2014028796-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC (US) 2014-02-20 WO claimed
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof Ensysce Biosciences Inc. (US) 2026-04-14 US disclosed
EP-4673430-A2 PHENYLALKYLAMINE PRODRUGS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
EP-4673127-A1 DEUTERATED AND FLUORINATED EMPATHOGENS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
US-20250388529-A1 N-Substituted Phenylalkylamines and Their Use as Therapeutic Agents ALEXANDER SHULGIN RES INSTITUTE INC (US) 2025-12-25 US disclosed
US-12465578-B2 Substituted alpha-ethyl phenylalkylamines ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) 2025-11-11 US disclosed
EP-4618981-A1 COMBINATIONS OF MONOAMINE OXIDASE INHIBITORS AND SEROTONIN RECEPTOR AGONISTS AND THEIR THERAPEUTIC USE Remedi, Inc. (US) 2025-09-24 EP disclosed
US-8017050-B2 Water purification membranes with improved fouling resistance BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-09-13 US disclosed
EP-2318126-A2 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-05-11 EP disclosed
WO-2011005258-A1 POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-01-13 WO disclosed
US-20100059433-A1 POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-03-11 US disclosed
US-20100051538-A1 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-03-04 US disclosed
WO-2010006196-A2 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388529-A1 N-Substituted Phenylalkylamines and Their Use as Therapeutic Agents CNR2, CNR1, HCN3 MMP1 3353/4885CYP3A4 994/4885FOS 1575/4885
US-12465578-B2 Substituted alpha-ethyl phenylalkylamines PNMT, SLC18A2, SLC1A2 MMP1 4155/4885CYP3A4 1057/4885FOS 4811/4885
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS HTR1A, HTR2A, HTR3A MMP1 4720/4885CYP3A4 2453/4885FOS 1847/4885
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof OPRK1, OPRL1, OPRM1 MMP1 82/4885CYP3A4 45/4885FOS 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.