Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | MMP1 | P03956 | 1/20 | 0.71 |
| ▸ | FOS | P01100 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | JUN | P05412 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695436 | 0.87 | ALOX15 (0.66) | CYP3A4MMP1FOSTTRJUN | |
| SCHEMBL7298435 | 0.87 | LDHA (0.58) | CYP3A4MMP1FOSTTRJUN | |
| SCHEMBL10776070 | 0.87 | LDHA (0.58) | CYP3A4MMP1FOSTTRJUN | |
| SCHEMBL7290411 | 0.87 | LDHA (0.58) | CYP3A4MMP1FOSTTRJUN | |
| Hydrochloric Acid SCHEMBL11696571 | 0.86 | ALOX15 (0.64) | CYP3A4MMP1FOSTTRJUN | |
| 3-O-Methyl-Alpha-Methyldopamine SCHEMBL9434236 | 0.83 | FOS (0.75) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL31677395 | 0.83 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL21028109 | 0.83 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL30334899 | 0.83 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN | |
| (+)-Secoisolariciresinol SCHEMBL325398 | 0.83 | CYP3A4 (1.00) | CYP3A4MMP1FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906100-B2 | Compounds and compositions derived from olives and methods of the use thereof | LAVIPHARM S.A. (GR) | 2005-06-14 | — | — | US | disclosed |
| EP-1474130-A2 | USE OF COMPOUNDS AND COMPOSITIONS DERIVED FROM OLIVES FOR PROTECTING CELLS AGAINST DNA DAMAGE | LAVIPHARM S.A. (GR) | 2004-11-10 | — | — | EP | disclosed |
| US-20030185921-A1 | COMPOUNDS AND COMPOSITIONS DERIVED FROM OLIVES AND METHODS OF USE THEREOF | THALLIUM HOLDING COMPANY, LLC | 2003-10-02 | — | — | US | disclosed |
| WO-2003066034-A2 | USE OF COMPOUNDS AND COMPOSITIONS DERIVED FORM OLIVES FOR PROTECTING CELLS AGAINST DNA DAMAGE | LAVIPHARM S.A. (GR) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185921-A1 | COMPOUNDS AND COMPOSITIONS DERIVED FROM OLIVES AND METHODS OF USE THEREOF | OGG1, SOD3, LIG3 | CYP3A4 4148/4885MMP1 401/4885FOS 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.