SCHEMBL4436459

SCHEMBL4436459

O=C(Cl)c1cccc(S(=O)(=O)c2ccccc2)c1C(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.44
MMP2 P08253 5/20 0.44
MMP9 P14780 5/20 0.44
MMP8 P22894 5/20 0.44
MMP13 P45452 5/20 0.44
MMP12 P39900 4/20 0.44
MMP14 P50281 4/20 0.44
MMP16 P51512 4/20 0.44
MMP3 P08254 3/20 0.44
MMP1 P03956 3/20 0.44
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29676384 0.79 NPSR1 (0.47) HTR6MMP2MMP9MMP8MMP13
SCHEMBL34677 0.79 NPSR1 (0.47) HTR6MMP2MMP9MMP8MMP13
SCHEMBL8747597 0.79 ALDH1A1 (0.42) MMP2MMP9MMP8MMP13MMP1
SCHEMBL628149 0.79 ALDH1A1 (0.42) MMP2MMP9MMP8MMP13MMP1
SCHEMBL9751876 0.77 HTR6 (0.45) HTR6MMP2MMP9MMP8MMP13
SCHEMBL505289 0.74 MMP2 (0.58) HTR6MMP2MMP9MMP8MMP13
SCHEMBL8966630 0.74 ALDH1A1 (0.50) MMP2MMP9MMP8MMP13MMP12
SCHEMBL22652933 0.73 GAA (0.48) MMP2MMP9MMP8MMP13MMP12
SCHEMBL893277 0.73 ALDH1A1 (0.56) MMP2TSHRPOLBALDH1A1ALOX15
SCHEMBL8982817 0.72 MMP2 (0.53) HTR6MMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191137-A1 THERMOPLASTIC COMPOSITIONS AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-06-13 US disclosed
CN-117043269-A Thermoplastic composition and use thereof 高新特殊工程塑料全球技术有限公司 2023-11-10 CN disclosed
WO-2021055267-A1 METHOD OF PREPARING POLYMER PARTICLES AND POLYMER PARTICLES PREPARED THEREBY SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-03-25 WO disclosed
EP-1763560-B1 POLYARYLATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2009-08-26 EP disclosed
US-20080174016-A1 Flexible Printed Wiring Board and Semiconductor Device MITSUI MINING & SMELTING CO., LTD. (JP) 2008-07-24 US disclosed
EP-1490420-B1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GEN ELECTRIC (US) 2007-08-01 EP disclosed
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP disclosed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US disclosed
US-20060160961-A1 Method for preparing copolyestercarbonates GENERAL ELECTRIC COMPANY (US) 2006-07-20 US disclosed
EP-1656409-A2 METHOD FOR PREPARING COPOLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2006-05-17 EP disclosed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO disclosed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US disclosed
US-20050049369-A1 Method for preparing copolyestercarbonates GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed
WO-2005019300-A2 METHOD FOR PREPARING COPOLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-03-03 WO disclosed
EP-1490420-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2004-12-29 EP disclosed
US-6812320-B2 PREPARING A HYDROXY-TERMINATED POLYESTER INTERMEDIATE; REACTING WITH PHOSGENE IN A REACTION MIXTURE COMPRISING WATER, A SUBSTANTIALLY WATER- IMMISCIBLE ORGANIC SOLVENT, AND A BASE TO PRODUCE BLOCK COPOLYESTERCARBONATE GENERAL ELECTRIC COMPANY 2004-11-02 US disclosed
US-6664366-B2 Interfacial polymerization of a 1,3-dihydroxybenzene moiety and aromatic dicarboxylic acid moieties to create polyesters free of anhydride linkages GENERAL ELECTRIC COMPANY 2003-12-16 US disclosed
US-20030195325-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY 2003-10-16 US disclosed
WO-2003082949-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2003-10-09 WO disclosed
US-20020156229-A1 Thermally stable polymers, method of preparation, and articles made therefrom GENERAL ELECTRIC COMPANY 2002-10-24 US disclosed