Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP8 | P22894 | 5/20 | 0.53 |
| ▸ | MMP12 | P39900 | 5/20 | 0.53 |
| ▸ | MMP13 | P45452 | 5/20 | 0.53 |
| ▸ | MMP14 | P50281 | 5/20 | 0.53 |
| ▸ | MMP16 | P51512 | 5/20 | 0.53 |
| ▸ | MMP3 | P08254 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148854 | 0.86 | HTR6 (0.45) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9751876 | 0.86 | HTR6 (0.45) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL505289 | 0.84 | MMP2 (0.58) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL8982817 | 0.81 | MMP2 (0.53) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL4455521 | 0.81 | MMP2 (0.53) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL364480 | 0.81 | HTR6 (0.55) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9772351 | 0.80 | MMP2 (0.49) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL27347915 | 0.80 | TSHR (0.50) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL27475173 | 0.80 | MMP2 (0.49) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL28977082 | 0.80 | LMNA (0.49) | MMP2MMP9MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100564432-C | The manufacture method of foams | OJI PAPER CO (JP) | 2009-12-02 | — | — | CN | disclosed |
| CN-100545198-C | Sheet-like foam and process for producing the same | OJI PAPER CO (JP) | 2009-09-30 | — | — | CN | disclosed |
| CN-101031610-A | Process for producing foam | OJI PAPER CO (JP) | 2007-09-05 | — | — | CN | disclosed |
| US-20060189549-A1 | Chalcone derivatives and their use to treat diseases | NI LIMING | 2006-08-24 | — | — | US | disclosed |
| CN-1823120-A | Foamed product in a sheet form and method for production thereof | OJI PAPER CO (JP) | 2006-08-23 | — | — | CN | disclosed |
| US-7094801-B2 | Chalcone derivatives and their use to treat diseases | ATHEROGENICS, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| CN-1214049-C | Process for producing ethylene/olefin interpolymers | EASTMAN CHEM CO (US) | 2005-08-10 | — | — | CN | disclosed |
| CN-1196719-C | Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization | EASTMAN CHEM CO (US) | 2005-04-13 | — | — | CN | disclosed |
| CN-1144821-C | Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization | 伊斯曼化学公司 | 2004-04-07 | — | — | CN | disclosed |
| US-20040048858-A1 | Chalcone derivatives and their use to treat diseases | CRABTREE ACQUISITION CO, LLC | 2004-03-11 | — | — | US | disclosed |
| CN-1416439-A | Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1416440-A | Procatalysts catalyst systems, and use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1394212-A | Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization | EASTMAN CHEM CO (US) | 2003-01-29 | — | — | CN | disclosed |
| CN-1367798-A | Process for producing ethylene/olefin interpolymers | EASTMAN CHEM CO (US) | 2002-09-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189549-A1 | Chalcone derivatives and their use to treat diseases | CYP46A1, HSD17B7, CYP11B2 | MMP2 1305/4885MMP9 1444/4885MMP8 953/4885 |
| US-20040048858-A1 | Chalcone derivatives and their use to treat diseases | CYP46A1, CYP11B1, HSD17B7 | MMP2 1326/4885MMP9 1343/4885MMP8 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.