Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 5/20 | 0.44 |
| ▸ | MMP12 | P39900 | 5/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.44 |
| ▸ | MMP14 | P50281 | 5/20 | 0.44 |
| ▸ | MMP16 | P51512 | 5/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040902 | 0.86 | MMP2 (0.53) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL3148854 | 0.83 | HTR6 (0.45) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL34677 | 0.79 | NPSR1 (0.47) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL29676384 | 0.79 | NPSR1 (0.47) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL18217890 | 0.79 | BCAT2 (0.49) | MMP2MMP9MMP8MMP13MMP1 | |
| SCHEMBL4436459 | 0.77 | HTR6 (0.44) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL7081730 | 0.76 | GAA (0.52) | LMNAKMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL28618805 | 0.75 | NPSR1 (0.46) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL505289 | 0.74 | MMP2 (0.58) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL11035205 | 0.74 | HTR6 (0.50) | HTR6LMNAKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444142-A4 | POLYQUINOLINE COPOLYMERS | — | 1991-10-16 | — | — | EP | disclosed |
| EP-0444142-A1 | POLYQUINOLINE COPOLYMERS | HITACHI CHEMICAL CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |