Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483549 | 0.80 | L3MBTL1 (0.50) | KDM4EALDH1A1BCAT2CA1CA2 | |
| SCHEMBL30752023 | 0.80 | CA1 (0.49) | KDM4EALDH1A1BCAT2JAK2JAK1 | |
| SCHEMBL2575446 | 0.80 | CA1 (0.49) | KDM4EALDH1A1BCAT2JAK2JAK1 | |
| SCHEMBL27953437 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1BCAT2JAK2JAK1 | |
| SCHEMBL364343 | 0.76 | BCAT2 (0.56) | KDM4EALDH1A1BCAT2JAK2JAK1 | |
| SCHEMBL29699541 | 0.75 | PABPC1 (0.56) | KDM4EALDH1A1BCAT2JAK2JAK1 | |
| SCHEMBL2698248 | 0.75 | LMNA (0.65) | KDM4EALDH1A1BCAT2PABPC1EIF4H | |
| SCHEMBL7108586 | 0.74 | NPC1 (0.53) | ALDH1A1BCAT2JAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL27374126 | 0.74 | BCAT2 (0.54) | KDM4EALDH1A1BCAT2JAK2JAK1 | |
| SCHEMBL4439614 | 0.74 | RXFP1 (0.50) | ALDH1A1CA1CA2SMN1; SMN2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200977-A2 | F1F0-ATPASE INHIBITORS AND RELATED METHODS | The Regents of the University of Michigan (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009036175-A2 | F1F0-ATPASE INHIBITORS AND RELATED METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-03-19 | — | — | WO | disclosed |