Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.55 |
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714236 | 0.85 | CES1 (0.55) | TGM2CES1ALDH1A1HPGDGFER | |
| SCHEMBL5330038 | 0.84 | TGM2 (0.53) | TGM2CES1ALDH1A1MAOAMAOB | |
| SCHEMBL22525915 | 0.83 | CASP3 (0.50) | TGM2CES1ALDH1A1HPGDGFER | |
| SCHEMBL16111115 | 0.83 | CES1 (0.53) | TGM2CES1ALDH1A1MAOAMAOB | |
| SCHEMBL18418044 | 0.82 | ACVR1 (0.51) | TGM2CES1ALDH1A1HPGDGFER | |
| SCHEMBL12120564 | 0.82 | HPGD (0.49) | TGM2CES1ALDH1A1HPGDGFER | |
| SCHEMBL2707210 | 0.82 | ACVR1 (0.51) | TGM2CES1ALDH1A1HPGDGFER | |
| SCHEMBL1767901 | 0.82 | TGM2 (0.50) | TGM2CES1ALDH1A1MAOAMAOB | |
| SCHEMBL11081844 | 0.82 | MAOA (0.47) | TGM2CES1ALDH1A1HPGDMAOA | |
| SCHEMBL22525914 | 0.81 | CASP3 (0.53) | ALDH1A1HPGDGFERHSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852031-A | 2, 3-Disubstituted quinazolinone compound and preparation method thereof | 赣南师范大学 | 2024-10-29 | — | — | CN | claimed |
| CN-1884264-A | Method for synthesizing 2-methyl-3-hydroxy-6-isopropyl quinolyl-4-carboxylic acid | LUCKY SHENYANG SCIENCE AND TEC (CN) | 2006-12-27 | — | — | CN | claimed |
| CN-1765885-A | 2-methyl-3-hydroxy-6-isopropylquinoline-4-carboxyl acid preparation method | CHINA LUCKY FILM CORP (CN) | 2006-05-03 | — | — | CN | claimed |
| CN-115974759-B | Compound with antibacterial use | 中国医学科学院药物研究所 | 2025-06-17 | — | — | CN | disclosed |
| CN-118852031-A | 2, 3-Disubstituted quinazolinone compound and preparation method thereof | 赣南师范大学 | 2024-10-29 | — | — | CN | disclosed |
| US-11052092-B2 | N-{[2-(piperidin-1-yl)phenyl](phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating autoimmune diseases | GENFIT (FR) | 2021-07-06 | — | — | US | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| CN-108853102-B | Condensed acridine derivatives acting on Dectin-1 and uses thereof | 北京大学 | 2021-04-09 | — | — | CN | disclosed |
| US-20200048195-A1 | SUBSTITUTED PYRROLIDINE CARBOXAMIDE COMPOUNDS | Epizyme, Inc. | 2020-02-13 | — | — | US | disclosed |
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-11-19 | — | — | US | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| US-6541470-B1 | Have a potent antiviral activity against picornaviruses and rotaviruses. | MARUISHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| EP-1081138-A1 | 1,2-disubstituted 1,4-dihydro-4-oxoquinoline compounds | Maruishi Pharmaceutical Co., Ltd. (JP) | 2001-03-07 | — | — | EP | disclosed |
| US-5872115-A | COMPOUNDS FOR TREATMENT OF HYPERCHOLESTEROLEMIA, ISCHEMIC HEART DISEASE, CEREBROVASCULAR DISEASE OR ATHEROSCLEROSIS | GRELAN PHARMACEUTICAL CO. LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| US-5817810-A | CHARGE TRANSFER AGENTS; ELECTROPHOTOSENSITIVITY | MITA INDUSTRIAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5616441-A | AS ELECTRON TRANSFERRING COMPOUND; INCREASED PHOTOSENSITIVITY; WEAR AND HEAT RESISTANCE; SOLVENT SOLUBILITY; BINDER COMPATABILITY; COPIERS; LASER PRINTERS | MITA INDUSTRIAL CO., LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |
| EP-0708375-A1 | Tryptanthrine derivative and electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
| CN-1079464-A | Treatment comprises the preparation method of the valuable indolone of illness of cholinergic function reduction and the derivative of indole dione | ASTRA AB (SE) | 1993-12-15 | — | — | CN | disclosed |
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11052092-B2 | N-{[2-(piperidin-1-yl)phenyl](phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)acetamide derivatives and related compounds as ROR-gamma modulators for treating autoimmune diseases | RORA, RORC, RORB | TGM2 185/4885CES1 733/4885ALDH1A1 118/4885 |
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | AADAC, NFKBIA, NOD2 | TGM2 566/4885CES1 289/4885ALDH1A1 1598/4885 |
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | TGM2 1964/4885CES1 1955/4885ALDH1A1 1575/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | TGM2 2210/4885CES1 1795/4885ALDH1A1 1125/4885 |
| US-20200048195-A1 | SUBSTITUTED PYRROLIDINE CARBOXAMIDE COMPOUNDS | SMYD3, SMYD2, SMURF2 | TGM2 2061/4885CES1 3403/4885ALDH1A1 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.