Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 8/20 | 0.55 |
| ▸ | CA2 known ✓ | P00918 | 8/20 | 0.55 |
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.55 |
| ▸ | CA12 known ✓ | O43570 | 6/20 | 0.38 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.33 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL2099839 | 1.00 | — | — | |
| Ethylene SCHEMBL2135882 | 0.95 | CA1 (0.50) | CA1CA2CA4TSHRATM | |
| Ethylene SCHEMBL11591128 | 0.95 | CA1 (0.50) | CA1CA2CA4TSHRATM | |
| Ethylene SCHEMBL3697216 | 0.95 | CA1 (0.50) | CA1CA2CA4TSHRATM | |
| Ethylene SCHEMBL3687908 | 0.95 | CA1 (0.50) | CA1CA2CA4TSHRATM | |
| Ethylene SCHEMBL27637313 | 0.91 | CA1 (0.46) | CA1CA2CA4TSHRATM | |
| SCHEMBL29742330 | 0.89 | CA1 (0.67) | CA1CA2CA4TSHRATM | |
| SCHEMBL36485 | 0.89 | CA1 (0.67) | CA1CA2CA4TSHRATM | |
| SCHEMBL451236 | 0.89 | — | — | |
| SCHEMBL23573895 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552219-B | Sodium (3-allylthiourea) (thio) methyl mercaptide and preparation method thereof | 陕西科技大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-112552219-A | Sodium (3-allylthiourea) (thio) methyl mercaptide and preparation method thereof | 陕西科技大学 | 2021-03-26 | — | — | CN | disclosed |
| EP-1517859-A4 | TREATING MICRO-ORGANISMS IN WATER USING BORON CONDITIONED ENZYMES | NOVAPHARM RES AUSTRALIA (AU) | 2009-06-17 | — | — | EP | disclosed |
| US-7347941-B2 | Treating micro-organisms in water using boron conditioned enzymes and composition therefor | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) | 2008-03-25 | — | — | US | disclosed |
| US-20050242029-A1 | Treating micro-organisms in water using boron conditioned enzymes | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) | 2005-11-03 | — | — | US | disclosed |
| EP-1517859-A1 | TREATING MICRO-ORGANISMS IN WATER USING BORON CONDITIONED ENZYMES | NOVAPHARM RESEARCH (AUSTRALIA) PTY. LIMITED (AU) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002896-A1 | TREATING MICRO-ORGANISMS IN WATER USING BORON CONDITIONED ENZYMES | NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) | 2004-01-08 | — | — | WO | disclosed |