Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sulfamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamate SCHEMBL6466728 | 0.92 | — | — | |
| Sulfamate SCHEMBL5187379 | 0.88 | — | — | |
| Sulfamate SCHEMBL5595588 | 0.88 | — | — | |
| Sulfamate SCHEMBL29413822 | 0.79 | — | — | |
| Sulfamate SCHEMBL11009323 | 0.79 | — | — | |
| Sulfamate SCHEMBL11400 | 0.78 | — | — | |
| Sulfamate SCHEMBL2545884 | 0.78 | CA1 (1.00) | — | |
| Sulfamate SCHEMBL285371 | 0.78 | — | — | |
| Sulfamate SCHEMBL28315208 | 0.75 | — | — | |
| Sulfamate SCHEMBL21291897 | 0.75 | CA1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005671-B2 | Concentrated aqueous bromine solutions and their preparation | ALBEMARLE CORPORATION (US) | 2015-04-14 | — | — | US | claimed |
| EP-1786266-B1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORP (US) | 2014-12-03 | — | — | EP | claimed |
| US-20090053327-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2009-02-26 | — | — | US | claimed |
| US-9005671-B2 | Concentrated aqueous bromine solutions and their preparation | ALBEMARLE CORPORATION (US) | 2015-04-14 | — | — | US | disclosed |
| US-9005671-B2 | Concentrated aqueous bromine solutions and their preparation | ALBEMARLE CORPORATION (US) | 2015-04-14 | — | — | US | disclosed |
| EP-1786266-B1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORP (US) | 2014-12-03 | — | — | EP | disclosed |
| CN-100577013-C | Concentrated aqueous bromine solutions and preparation thereof | ALBEMARLE CORP | 2010-01-06 | — | — | CN | disclosed |
| US-20090053327-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090053327-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| CN-101010007-A | Concentrated aqueous bromine solutions and their preparation | ALBEMARLE CORP (US) | 2007-08-01 | — | — | CN | disclosed |
| EP-1786266-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1786266-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006029354-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006029354-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |