Water

Water

SCHEMBL445598

O.[CaH2].[Mn].[Pr]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL22582402 0.89
Water SCHEMBL10762306 0.87
SCHEMBL2297907 0.87
Water SCHEMBL28210431 0.75
Water SCHEMBL16241330 0.75
Water SCHEMBL23300491 0.75
SCHEMBL28122554 0.75
SCHEMBL445597 0.75
Water SCHEMBL28544604 0.75
Water SCHEMBL28264912 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102683582-A Method for manufacturing high sensitivity magnetic sensor chip BINGJUN QU 2012-09-19 CN claimed
CN-100495683-C A method for making resistor random memory unit array INST OF PHYSICS CAS (CN) 2009-06-03 CN claimed
CN-110275694-B Apparatus for generating sum of products and method of operating the same 旺宏电子股份有限公司 2023-08-22 CN disclosed
CN-107946461-B Ferroelectric resistive random access memory and writing method, reading method and preparation method thereof 南方科技大学 2021-10-19 CN disclosed
CN-110275694-A For generating the device and its operating method of long-pending item sum 旺宏电子股份有限公司 2019-09-24 CN disclosed
CN-106252204-B A method of by huge magnetic resistance manganese-salt phosphating in graphics of nanometer dimension 复旦大学 2019-05-31 CN disclosed
CN-104752455-B Nonvolatile semiconductor memory member 爱思开海力士有限公司 2019-05-10 CN disclosed
CN-107946461-A Ferroelectric resistive random access memory and writing method, reading method and preparation method thereof 南方科技大学 2018-04-20 CN disclosed
CN-106252204-A A kind of by huge magnetic resistance manganese-salt phosphating in the method for graphics of nanometer dimension 复旦大学 2016-12-21 CN disclosed
US-8493771-B2 Non-volatile memory device ion barrier UNITY SEMICONDUCTOR CORPORATION (US) 2013-07-23 US disclosed
US-8339867-B2 Fuse elements based on two-terminal re-writeable non-volatile memory UNITY SEMICONDUCTOR CORPORATION (US) 2012-12-25 US disclosed
US-20080144357-A1 Method for sensing a signal in a two-terminal memory array having leakage current UNITY SEMICONDUCTOR CORPORATION (US) 2008-06-19 US disclosed
US-7379364-B2 Sensing a signal in a two-terminal memory array having leakage current UNITY SEMICONDUCTOR CORPORATION 2008-05-27 US disclosed
US-7372753-B1 Two-cycle sensing in a two-terminal memory array having leakage current UNITY SEMICONDUCTOR CORPORATION 2008-05-13 US disclosed
CN-101174672-A Memory cell and process thereof MACRONIX INT CO LTD (CN) 2008-05-07 CN disclosed
US-20080094929-A1 TWO-CYCLE SENSING IN A TWO-TERMINAL MEMORY ARRAY HAVING LEAKAGE CURRENT III HOLDINGS 1, LLC 2008-04-24 US disclosed
US-20080094876-A1 SENSING A SIGNAL IN A TWO-TERMINAL MEMORY ARRAY HAVING LEAKAGE CURRENT UNITY SEMICONDUCTOR, INC. 2008-04-24 US disclosed
US-20080084727-A1 Scaleable memory systems using third dimension memory UNITY SEMICONDUCTOR, INC. 2008-04-10 US disclosed
CN-101079395-A A method for making resistor random memory unit array INST OF PHYSICS CAS (CN) 2007-11-28 CN disclosed
US-20070105390-A1 Oxygen depleted etching process UNITY SEMICONDUCTOR, INC. 2007-05-10 US disclosed