Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4461982 | 0.79 | MAPK3 (0.36) | FGFR4EGFRMAPK1MAPK3 | |
| Sulfuric Acid SCHEMBL5242033 | 0.74 | HTT (0.49) | MAPTRXFP1TDP1KMT2APOLB | |
| Sulfuric Acid SCHEMBL5244029 | 0.72 | MAPK3 (0.41) | EGFRMAPK1MAPK3 | |
| SCHEMBL4461476 | 0.69 | RXFP1 (0.42) | MAPTRXFP1TDP1KMT2ACYP1A2 | |
| SCHEMBL8079170 | 0.67 | HTT (0.55) | MAPTRXFP1TDP1KMT2AL3MBTL1 | |
| SCHEMBL28269774 | 0.66 | L3MBTL1 (0.49) | MAPTTDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL5833719 | 0.65 | LMNA (0.43) | MAPTRXFP1TDP1KMT2ACYP1A2 | |
| SCHEMBL24313998 | 0.63 | RXFP1 (0.38) | MAPTRXFP1TDP1KMT2ACYP1A2 | |
| SCHEMBL7515186 | 0.63 | TDP1 (0.36) | JAK3MAPTBTKRXFP1TDP1 | |
| SCHEMBL1813599 | 0.63 | NPC1 (0.46) | MAPTRXFP1TDP1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828253-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | claimed |
| US-20060094844-A1 | Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2006-05-04 | — | — | US | claimed |
| WO-2006046255-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | claimed |
| US-7560522-B2 | Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-07-14 | — | — | US | disclosed |
| US-20070213489-A1 | Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof | PATIL PRERANA M | 2007-09-13 | — | — | US | disclosed |
| EP-1828253-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | disclosed |
| EP-1828255-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006046254-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006046255-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | disclosed |