Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681590 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2LMNAALDH1A1ALOX5 | |
| SCHEMBL349307 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2LMNAALDH1A1ALOX5 | |
| SCHEMBL349308 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2LMNAALDH1A1ALOX5 | |
| SCHEMBL350063 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2LMNAALDH1A1ALOX5 | |
| SCHEMBL350064 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2LMNAALDH1A1ALOX5 | |
| SCHEMBL349323 | 0.80 | ITGB3 (0.36) | ITGB3ITGA2LMNA | |
| SCHEMBL2850903 | 0.74 | NPC1 (0.57) | ITGB3ITGA2ALDH1A1SMN1; SMN2CYP26A1 | |
| SCHEMBL3679858 | 0.73 | CA2 (0.48) | ITGB3ITGA2ALOX5SMN1; SMN2HTT | |
| SCHEMBL7173218 | 0.72 | SMN1; SMN2 (0.74) | ITGB3LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7175551 | 0.72 | SMN1; SMN2 (0.74) | ITGB3LMNAALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647882-B2 | Chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-8268631-B2 | Chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20090229352-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090229352-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | BCAT2, BCAT1, SLC43A1 | ITGB3 3802/4885ITGA2 3095/4885LMNA 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.