Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.34 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.34 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.34 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.34 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.34 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.34 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.34 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347285 | 0.92 | ITGB3 (0.42) | ITGB3ITGA2MMP2LMNAMAPK1 | |
| SCHEMBL4455801 | 0.85 | MMP2 (0.45) | MMP2KMOMAPK1 | |
| SCHEMBL4462369 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2LMNA | |
| SCHEMBL3681590 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2LMNA | |
| SCHEMBL3679858 | 0.74 | CA2 (0.48) | ITGB3ITGA2MAPK1ACEECE1 | |
| SCHEMBL349307 | 0.71 | ITGB3 (0.58) | ITGB3ITGA2LMNA | |
| SCHEMBL349308 | 0.71 | ITGB3 (0.58) | ITGB3ITGA2LMNA | |
| SCHEMBL8421592 | 0.70 | MMP2 (0.58) | MMP2LMNAACE | |
| SCHEMBL350064 | 0.68 | ITGB3 (0.62) | ITGB3ITGA2LMNA | |
| SCHEMBL350063 | 0.68 | ITGB3 (0.62) | ITGB3ITGA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | BCAT2, BCAT1, SLC43A1 | ITGB3 3802/4885ITGA2 3095/4885MMP2 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.