Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386182 | 0.87 | BRD4 (0.33) | BRD4CREBBPPARP1PTAFRS1PR4 | |
| SCHEMBL1583270 | 0.83 | DPP4 (0.39) | DRD2 | |
| SCHEMBL29594761 | 0.82 | BRD4 (0.36) | BRD4CREBBPPARP1PTAFRS1PR4 | |
| SCHEMBL1807786 | 0.82 | BRD4 (0.36) | BRD4CREBBPPARP1PTAFRS1PR4 | |
| SCHEMBL2389483 | 0.81 | ACHE (0.37) | BRD4CREBBP | |
| Lithium SCHEMBL30438304 | 0.81 | BRD4 (0.36) | BRD4CREBBPPARP1PTAFRS1PR4 | |
| SCHEMBL29040664 | 0.81 | BRD4 (0.36) | BRD4CREBBPPARP1PTAFRS1PR4 | |
| SCHEMBL28148566 | 0.81 | BRD4 (0.36) | BRD4CREBBPPARP1PTAFRS1PR4 | |
| SCHEMBL4198923 | 0.81 | PTAFR (0.34) | PTAFRNPC1LMNATP53RAB9A | |
| SCHEMBL2707579 | 0.79 | BRD4 (0.35) | BRD4CREBBPPARP1PTAFRS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100575324-C | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH | 2009-12-30 | — | — | CN | disclosed |
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| US-7241903-B2 | Metallocenes, use in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| EP-1334107-B1 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| CN-1249096-C | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2006-04-05 | — | — | CN | disclosed |
| EP-1397371-B1 | METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| US-6872843-B2 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| CN-1590355-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2005-03-09 | — | — | CN | disclosed |
| CN-1590422-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2005-03-09 | — | — | CN | disclosed |
| US-20040171855-A1 | Metallocenes, use in catalyst system for producing olefin polymers | EQUISTAR CHEMICALS, LP | 2004-09-02 | — | — | US | disclosed |
| EP-1397371-A1 | METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Polyolefine GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | EQUISTAR CHEMICALS, LP | 2004-02-05 | — | — | US | disclosed |
| US-6627764-B1 | Titanium, hafnium or zirconium indenyl halide complexes; coordination catalysts | BASELL POLYOLEFINE GMBH (DE) | 2003-09-30 | — | — | US | disclosed |
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| CN-1433435-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-07-30 | — | — | CN | disclosed |
| WO-2003000706-A1 | METALLOCENES, USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171855-A1 | Metallocenes, use in catalyst system for producing olefin polymers | H1-4, H1-0, H1-10 | BRD4 2213/4885CREBBP 4847/4885PARP1 657/4885 |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | BRD4 1223/4885CREBBP 2360/4885PARP1 421/4885 |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | SOAT2, NOTUM, SOAT1 | BRD4 1062/4885CREBBP 3466/4885PARP1 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.