SCHEMBL4466119

SCHEMBL4466119

CO[Si](CCCNC(=S)NCCN(C)C)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA12 O43570 3/20 0.43
CA9 Q16790 1/20 0.43
ACHE P22303 1/20 0.42
PKM P14618 1/20 0.41
ALDH1A1 P00352 3/20 0.41
POLB P06746 2/20 0.41
RECQL P46063 1/20 0.41
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.38
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SSTR2 P30874 1/20 0.34
SSTR4 P31391 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19827963 0.87 GAA (0.47) ALDH1A1LMNAGAAKMT2A
SCHEMBL19822480 0.80 ALDH1A1 (0.50) ALDH1A1GAAKMT2A
SCHEMBL19822469 0.80 MEN1 (0.47) ALDH1A1LMNAGAAKMT2ASMN1; SMN2
SCHEMBL19822468 0.80 QPCT (0.44) ALDH1A1LMNAGAAKMT2A
SCHEMBL10486780 0.79 CA1 (0.62) CA1CA2CA12CA9ACHE
SCHEMBL4459433 0.78 LMNA (0.45) ALDH1A1LMNAGAAKMT2A
SCHEMBL8083063 0.78 CYP2C9 (0.48) CA1CA2CA12CA9ALDH1A1
SCHEMBL19822470 0.78 KMT2A (0.44) ALDH1A1POLBLMNAGAAKMT2A
SCHEMBL19822477 0.76 ALDH1A1 (0.38) ALDH1A1POLBLMNAGAAKMT2A
SCHEMBL10481559 0.76 DNM1 (0.42) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2090145-B1 USE OF SILANE COMPOSITIONS FOR THE PRODUCTION OF MULTILAYER LAMINATES ATOTECH DEUTSCHLAND GMBH (DE) 2014-05-21 EP disclosed
EP-2090145-A2 USE OF SILANE COMPOSITIONS FOR THE PRODUCTION OF MULTILAYER LAMINATES ATOTECH DEUTSCHLAND GMBH (DE) 2009-08-19 EP disclosed
WO-2008122427-A2 USE OF SILANE COMPOSITIONS FOR THE PRODUCTION OF MUTILAYER LAMINATES ATOTECH DEUTSCHLAND GMBH (DE) 2008-10-16 WO disclosed
EP-1978024-A1 Silane compositions comprising novel crosslinking agents ATOTECH DEUTSCHLAND GMBH (DE) 2008-10-08 EP disclosed