Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336648 | 0.87 | CRHBP (0.40) | TDP1PTPN1EPAS1TSHRSMN1; SMN2 | |
| SCHEMBL7392580 | 0.84 | TSHR (0.40) | TDP1PTPN1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7550828 | 0.84 | TSHR (0.49) | PTPN1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL29497739 | 0.81 | TDP1 (0.46) | TDP1TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20582958 | 0.81 | TDP1 (0.46) | TDP1TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL810810 | 0.81 | TSHR (0.49) | TDP1PTPN1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL31090816 | 0.81 | TSHR (0.49) | TDP1PTPN1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL40551 | 0.79 | TDP1 (0.49) | TDP1PTPN1EPAS1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3434984 | 0.78 | PTPN1 (0.46) | PTPN1SMN1; SMN2ALDH1A1MAPTALDH3A1 | |
| SCHEMBL8722119 | 0.78 | CTSB (0.45) | TDP1PTPN1EPAS1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836202-B1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARM INC (US) | 2016-12-21 | — | — | EP | disclosed |
| CN-101119993-B | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARM INC | 2015-03-04 | — | — | CN | disclosed |
| US-20090270449-A1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SCHLIENGER NATHALIE | 2009-10-29 | — | — | US | disclosed |
| US-7585877-B2 | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARMACEUTICALS, INC. | 2009-09-08 | — | — | US | disclosed |
| CN-101119993-A | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| WO-2006076317-A9 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARM INC (US) | 2007-09-27 | — | — | WO | disclosed |
| EP-1836202-A2 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | Acadia Pharmaceuticals Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2007092400-A1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| US-7199147-B2 | Rho kinase inhibitors | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20060173037-A1 | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARMACEUTICALS INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006076317-A2 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | ACADIA PHARMACEUTICALS INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060160845-A1 | Aminophenyl derivatives as selective androgen receptor modulators | ACADIA PHARMACEUTICALS INC. | 2006-07-20 | — | — | US | disclosed |
| US-20040138286-A1 | Rho kinase inhibitors | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1403255-A1 | Rho KINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173037-A1 | Aminophenyl derivatives as selective androgen receptor modulators | AR, NR5A1, ESRRA | TDP1 2425/4885PTPN1 1274/4885EPAS1 491/4885 |
| US-20090270449-A1 | AMINOPHENYL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, ESRRA | TDP1 2425/4885PTPN1 1274/4885EPAS1 491/4885 |
| US-20040138286-A1 | Rho kinase inhibitors | ROCK1, ROCK2, ARHGDIA | TDP1 1496/4885PTPN1 513/4885EPAS1 2195/4885 |
| US-20060160845-A1 | Aminophenyl derivatives as selective androgen receptor modulators | AR, NR5A1, ESRRA | TDP1 2425/4885PTPN1 1274/4885EPAS1 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.