SCHEMBL4474356

SCHEMBL4474356

CCCCCC[C@@H](O)C/C=C\CCC(CCCCC(=O)O)OCC(O)CO

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.66
FFAR4 Q5NUL3 2/20 0.66
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
FAAH O00519 3/20 0.53
DGKA P23743 1/20 0.49
PPARG P37231 4/20 0.45
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
MAPT P10636 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8532124 0.92 FFAR1 (0.60) FFAR1FFAR4FAAHDGKAPPARG
SCHEMBL8931485 0.89 FFAR1 (0.65) FFAR1FFAR4NFKB1NFKB2RELA
SCHEMBL28020113 0.89 FFAR1 (0.65) FFAR1FFAR4NFKB1NFKB2RELA
SCHEMBL11495230 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD
SCHEMBL10425363 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD
SCHEMBL11561334 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD
SCHEMBL27484916 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD
SCHEMBL10631927 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD
SCHEMBL9443658 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD
SCHEMBL8818527 0.87 FFAR4 (0.61) FFAR1FFAR4PPARGPTPN1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278350-B2 Agent for skin external use containing salt of ascorbic acid derivative, method for stabilizing the agent for skin external use, and stabilizer SHOWA DENKO K.K. (JP) 2012-10-02 US disclosed
EP-1660025-B1 COSMETIC COMPOSITION CONTAINING A POLYOXYETHYL COMBINATION AND A LIPOPEPTIDE SHOWA DENKO KK (JP) 2009-07-15 EP disclosed
US-20080311234-A1 Oil-in-Water Emulsified Composition, and External Preparation for Skin and Cosmetics Using the Composition SHOWA DENKO K.K. (JP) 2008-12-18 US disclosed
US-20080234224-A1 External Preparation For Skin SHOWA DENKO K.K. (JP) 2008-09-25 US disclosed
US-20070232687-A1 Agent for Skin External Use Containing Tocopherol Derivative, Ascorbic Acid Derivative and Surface Active Agent Having Lipopeptide Structure SHOWA DENKO K.K. (JP) 2007-10-04 US disclosed
US-20070140998-A1 Agent for skin external use containing salt of ascorbic acid derivative, method for stabilizing the agent for skin external use, and stabilizer SHOWA DENKO K.K. (JP) 2007-06-21 US disclosed
US-20060222616-A1 Cosmetic composition comprising a and a lipopeptide KANEKA CORPORATION (JP) 2006-10-05 US disclosed
US-20050220744-A1 Polysaccharide/functional compound complex SHOWA DENKO K.K. 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070140998-A1 Agent for skin external use containing salt of ascorbic acid derivative, method for stabilizing the agent for skin external use, and stabilizer CUTA, TTPA, RBP4 FFAR1 34/4885FFAR4 22/4885NFKB1 490/4885
US-20060222616-A1 Cosmetic composition comprising a and a lipopeptide CUTA, SMURF1, FABP4 FFAR1 22/4885FFAR4 73/4885NFKB1 2801/4885
US-20080311234-A1 Oil-in-Water Emulsified Composition, and External Preparation for Skin and Cosmetics Using the Composition CUTA, FPR1, FPR2 FFAR1 16/4885FFAR4 108/4885NFKB1 2245/4885
US-20070232687-A1 Agent for Skin External Use Containing Tocopherol Derivative, Ascorbic Acid Derivative and Surface Active Agent Having Lipopeptide Structure TTPA, GLA, CUTA FFAR1 875/4885FFAR4 861/4885NFKB1 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.