Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | F7 | P08709 | 2/20 | 0.58 |
| ▸ | F3 | P13726 | 2/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693884 | 1.00 | TERT (0.58) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28803423 | 0.89 | CES2 (0.57) | MAPTFAAHKMT2ALMNAMEN1 | |
| SCHEMBL21452297 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL21452029 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL21451223 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23950153 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23950132 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23950452 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL21448814 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL23572558 | 0.84 | TERT (0.63) | TERTPTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005447-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR REDUCING BODY FAT AND MODULATING FATTY ACID METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-01-01 | — | — | US | disclosed |
| US-7423066-B2 | Dietetics; use in treatment of obesity, for reducing body weight, modulating body lipid metabolism, and reducing food intake | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-09 | — | — | US | disclosed |
| US-20080103209-A1 | Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-01 | — | — | US | disclosed |
| EP-1677780-A4 | DIETARY AND OTHER COMPOSITIONS, COMPOUNDS, AND METHODS FOR REDUCING BODY FAT, CONTROLLING APPETITE, AND MODULATING FATTY ACID METABOLISM | UNIV CALIFORNIA (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1742626-A2 | COMPOUNDS AND METHODS FOR TREATING NON-INFLAMMATORY PAIN USING PPARALPHA AGONISTS | The Regents of The University of California (US) | 2007-01-17 | — | — | EP | disclosed |
| EP-1677780-A2 | DIETARY AND OTHER COMPOSITIONS, COMPOUNDS, AND METHODS FOR REDUCING BODY FAT, CONTROLLING APPETITE, AND MODULATING FATTY ACID METABOLISM | The Regents of the University of California (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005115370-A2 | COMPOUNDS AND METHODS FOR TREATING NON-INFLAMMATORY PAIN USING PPARALPHA AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050187254-A1 | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-08-25 | — | — | US | disclosed |
| US-20050154064-A1 | Dietary and other compositions, compounds, and methods for reducing body fat, controlling appetite, and modulating fatty acid metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-07-14 | — | — | US | disclosed |
| EP-1408945-A4 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR REDUCING BODY FAT AND MODULATING FATTY ACID METABOLISM | UNIV CALIFORNIA (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6911474-B2 | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-06-28 | — | — | US | disclosed |
| WO-2005046580-A2 | DIETARY AND OTHER COMPOSITIONS, COMPOUNDS, AND METHODS FOR REDUCING BODY FAT, CONTROLLING APPETITE, AND MODULATING FATTY ACID METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-26 | — | — | WO | disclosed |
| US-20050054730-A1 | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-03-10 | — | — | US | disclosed |
| WO-2005002524-A2 | COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES OF OLEOYLETHANOLAMIDE-LIKE COMPOUNDS AND MODULATORS OF PPARα | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-13 | — | — | WO | disclosed |
| EP-1408945-A2 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR REDUCING BODY FAT AND MODULATING FATTY ACID METABOLISM | The Regents of the University of California (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20030018081-A1 | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-01-23 | — | — | US | disclosed |
| WO-2002080860-A2 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR REDUCING BODY FAT AND MODULATING FATTY ACID METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103209-A1 | Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists | FAAH, CNR2, FAAH2 | TERT 4310/4885PTPN1 925/4885PPARG 6/4885 |
| US-20090005447-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR REDUCING BODY FAT AND MODULATING FATTY ACID METABOLISM | LIPC, FABP4, FASN | TERT 4546/4885PTPN1 4403/4885PPARG 80/4885 |
| US-20030018081-A1 | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism | LIPC, FABP4, FASN | TERT 4546/4885PTPN1 4403/4885PPARG 80/4885 |
| US-20050187254-A1 | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism | LIPC, FABP4, FASN | TERT 4546/4885PTPN1 4403/4885PPARG 80/4885 |
| US-20050054730-A1 | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha | PPARA, CNR2, CNR1 | TERT 4152/4885PTPN1 3880/4885PPARG 11/4885 |
| US-20050154064-A1 | Dietary and other compositions, compounds, and methods for reducing body fat, controlling appetite, and modulating fatty acid metabolism | FABP4, LIPC, FAAH | TERT 4829/4885PTPN1 4058/4885PPARG 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.