SCHEMBL448738

SCHEMBL448738

C=CC(=O)Oc1c(Br)cc(Br)cc1C(C)CC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
PPARA Q07869 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
THRA P10827 5/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30004700 1.00 THRB (0.35) THRBTSHRTDP1HSD17B10GABRA1
SCHEMBL30486245 0.86 GABRA1 (0.41) THRBTSHRHSD17B10GABRA1GABRB1
SCHEMBL447804 0.86 GABRA1 (0.41) THRBTSHRHSD17B10GABRA1GABRB1
SCHEMBL7065851 0.84 THRB (0.40) THRBTSHRHSD17B10L3MBTL1THRA
SCHEMBL3746023 0.82 TSHR (0.43) THRBTSHRTHRAALDH1A1KMT2A
SCHEMBL7065852 0.79 GPR35 (0.40) THRBTSHRTDP1HSD17B10GABRA1
SCHEMBL316904 0.79 HSD17B10 (0.42) THRBTSHRTDP1HSD17B10GABRA1
SCHEMBL7714546 0.77 THRB (0.36) THRBTSHRTDP1HSD17B10THRA
SCHEMBL7066169 0.76 MAPT (0.34) THRBTDP1HSD17B10GABRA1GABRB1
SCHEMBL7061577 0.74 GABRA1 (0.35) THRBTSHRGABRA1GABRB1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294800-A1 NOVEL URETHANE ACRYLATE COMPOSITION STRATASYS, INC. (US) 2024-09-05 US claimed
US-20240279508-A1 NOVEL DUAL CURE 3D PRINTING RESINS STRATASYS INC. 2024-08-22 US claimed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP claimed
EP-4363467-A1 NOVEL DUAL CURE 3D PRINTING RESINS Stratasys, Inc. (US) 2024-05-08 EP claimed
US-11891469-B2 Urethane acrylate composition STRATASYS, INC. (US) 2024-02-06 US claimed
WO-2023278202-A1 NOVEL URETHANE ACRYLATE COMPOSITION COVESTRO LLC (US) 2023-01-05 WO claimed
WO-2023278201-A1 NOVEL DUAL CURE 3D PRINTING RESINS COVESTRO LLC (US) 2023-01-05 WO claimed
US-20220411563-A1 NOVEL DUAL CURE 3D PRINTING RESINS STRATASYS INC. 2022-12-29 US claimed
US-20220411560-A1 NOVEL URETHANE ACRYLATE COMPOSITION STRATASYS INC. 2022-12-29 US claimed
US-8241755-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-14 US claimed
US-20110318538-A1 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
US-8034421-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-10-11 US claimed
US-8025934-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-27 US claimed
US-20100331442-A1 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY 2010-12-30 US claimed
US-20080253148-A1 Polymerizable Composition Comprising Low Molecular Weight Organic Component 3M INNOVATIVE PROPERTIES COMPANY 2008-10-16 US claimed
US-20060204676-A1 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US claimed
US-12552087-B2 Method of thermoforming film with structured surface and articles SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-02-17 US disclosed
EP-3917445-B1 METHODS OF MAKING AND POSTPROCESSING ORTHODONTIC ARTICLES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-11-05 EP disclosed
US-6416838-B1 CROSSLINKABLE MIXTURE CONTAINING UNSATURATED ESTER AND AMIDE MONOMERS, POLYMER HAVING SPECIFIED MOLECULAR RANGE AND SURFACE-MODIFIED PARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2002-07-09 US disclosed
WO-2001030872-A1 COMPOSITIONS AND ARTICLES MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552087-B2 Method of thermoforming film with structured surface and articles TPM3, TLL1, TPM4 THRB 2164/4885TSHR 962/4885TDP1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.