Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 12/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL29182965 | 0.94 | AKR1C3 (0.46) | AKR1C3AKR1C2PTGS1AKR1C1HTR1A | |
| SCHEMBL1574429 | 0.89 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS1AKR1C1HTR1A | |
| SCHEMBL510548 | 0.82 | ALDH1A1 (0.56) | AKR1C3AKR1C2PTGS1AKR1C1HTR1A | |
| SCHEMBL7705115 | 0.82 | ALDH1A1 (0.56) | AKR1C3AKR1C2PTGS1AKR1C1HTR1A | |
| SCHEMBL819392 | 0.82 | LMNA (0.61) | AKR1C3AKR1C2PTGS1AKR1C1HTR1A | |
| SCHEMBL65737 | 0.81 | LMNA (0.59) | HTR1AADRA1AALDH1A1GAALMNA | |
| SCHEMBL67237 | 0.81 | LMNA (0.59) | HTR1AADRA1AALDH1A1GAALMNA | |
| SCHEMBL20769804 | 0.81 | LMNA (0.59) | HTR1AADRA1AALDH1A1GAALMNA | |
| SCHEMBL1715 | 0.81 | LMNA (0.59) | HTR1AADRA1AALDH1A1GAALMNA | |
| SCHEMBL29757088 | 0.81 | LMNA (0.59) | HTR1AADRA1AALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826888-A | STORAGE STABLE, DISCOLORATION INHIBITION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-02 | — | — | US | claimed |
| US-7582632-B2 | Tri(cyclo) substituted amide compounds | PROSIDION LIMITED (GB) | 2009-09-01 | — | — | US | disclosed |
| US-20070281946-A1 | TRI(CYCLO) SUBSTITUTED AMIDE COMPOUNDS | OSI PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-5047442-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an alpha-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0201903-B1 | PHOTOPOLYMERIZABLE COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-4826888-A | STORAGE STABLE, DISCOLORATION INHIBITION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4777190-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an α-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0201903-A2 | Photopolymerizable composition | MITSUBISHI RAYON CO., LTD. (JP) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281946-A1 | TRI(CYCLO) SUBSTITUTED AMIDE COMPOUNDS | IAPP, GPR119, SLC5A1 | AKR1C3 921/4885AKR1C2 590/4885PTGS1 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.