Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635370 | 0.87 | KMT2A (0.39) | KMT2ANOS3NOS2RXFP1ALDH1A1 | |
| SCHEMBL31200696 | 0.84 | ALDH1A1 (0.43) | RXFP1ALDH1A1ALOX15ALOX12GAA | |
| SCHEMBL21691999 | 0.80 | HSPA5 (0.48) | ALDH1A1HSPA5CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8629559 | 0.78 | HSPA5 (0.38) | KMT2AALDH1A1GAAMAPK1GRIN2D | |
| SCHEMBL1262846 | 0.77 | KMT2A (0.36) | KMT2ANOS3NOS2RXFP1ALDH1A1 | |
| SCHEMBL13683276 | 0.76 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10477405 | 0.76 | PTPN1 (0.39) | KMT2AALDH1A1ALOX15ALOX12CYP2C9 | |
| SCHEMBL3658093 | 0.76 | GABRA1 (0.39) | HPGDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20670040 | 0.75 | KMT2A (0.31) | KMT2ARXFP1ALDH1A1GAAHPGD | |
| SCHEMBL8082167 | 0.74 | NOS3 (0.38) | KMT2ANOS3NOS2RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218153-A | A kind of preparation method of midbody compound 2,6- diethyl -4- methylbenzene malonate | 江苏丰山集团股份有限公司 | 2019-09-10 | — | — | CN | claimed |
| US-11053228-B2 | Condensed cyclic compound, composition including the condensed cyclic compound, and organic light-emitting device including the condensed cyclic compound | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-07-06 | — | — | US | disclosed |
| CN-110950778-A | Process and catalyst system for preparing aromatic malononitrile | 安徽省化工研究院 | 2020-04-03 | — | — | CN | disclosed |
| US-20200031812-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND | SAMSUNG SDI CO., LTD. (KR) | 2020-01-30 | — | — | US | disclosed |
| CN-110218153-A | A kind of preparation method of midbody compound 2,6- diethyl -4- methylbenzene malonate | 江苏丰山集团股份有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-110218153-A | A kind of preparation method of midbody compound 2,6- diethyl -4- methylbenzene malonate | 江苏丰山集团股份有限公司 | 2019-09-10 | — | — | CN | disclosed |
| US-7605111-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7459414-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| CN-1272324-C | Novel herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-30 | — | — | CN | disclosed |
| US-20050187110-A1 | mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants | MAETZKE THOMAS (CH) | 2005-08-25 | — | — | US | disclosed |
| US-20050164883-A1 | agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides | MAETZKE THOMAS (CH) | 2005-07-28 | — | — | US | disclosed |
| US-6894005-B1 | Heterocyclic compound containing phenyl groups; postemergence herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| EP-1210333-B1 | p-Tolyl-heterocycles as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-11-17 | — | — | EP | disclosed |
| CN-1514829-A | Novel herbicides | �����ɷ� | 2004-07-21 | — | — | CN | disclosed |
| EP-1185506-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARATION OF HERBICIDES | Syngenta Participations AG (CH) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000078712-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARTION OF HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| EP-0718291-B1 | Method for the preparation of triazole compounds | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5567825-A | Method for the preparation of a triazole compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-10-22 | — | — | US | disclosed |
| EP-0718291-A1 | Method for the preparation of triazole compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053228-B2 | Condensed cyclic compound, composition including the condensed cyclic compound, and organic light-emitting device including the condensed cyclic compound | CCNL2, ARL1, CRY1 | KMT2A 1275/4885NOS3 4314/4885NOS2 3697/4885 |
| US-20050164883-A1 | agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides | DDT, SULT2A1, GSTA1 | KMT2A 650/4885NOS3 2679/4885NOS2 2280/4885 |
| US-20200031812-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND | CCNL2, ARL1, CRY1 | KMT2A 1275/4885NOS3 4314/4885NOS2 3697/4885 |
| US-20050187110-A1 | mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants | PIN1, GMDS, DDT | KMT2A 1469/4885NOS3 2883/4885NOS2 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.